STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
naryaRING finger protein narya; Required for the formation of DNA double-strand breaks (DSBs) together with nenya and vilya during the meiotic recombination process. Plays a role in DSBs processing into crossovers. Plays a redundant role with nenya in chromosome segregation during female meiosis. (211 aa)    
Predicted Functional Partners:
vilya
Vilya (vilya) encodes a meiosis-specific ring-domain-containing protein that is required for programmed meiotic double-strand break formation. It also functions as a component of the recombination nodule.
   
 
 0.878
CG31807
IP04788p; Ubiquitin-protein transferase activity; zinc ion binding; ubiquitin protein ligase activity. It is involved in the biological process described with: protein ubiquitination; interstrand cross-link repair.
   
  
 0.800
CG32533
LD31543p; RNA binding; helicase activity. It is involved in the biological process described with: nuclear-transcribed mRNA catabolic process, nonsense-mediated decay.
   
  
 0.670
m-cup
Mann-cup, isoform A; It is involved in the biological process described with: protein ubiquitination.
    
 
 0.666
CG5334
Ubiquitin-protein transferase activity; zinc ion binding; metal ion binding; ubiquitin protein ligase activity. It is involved in the biological process described with: protein polyubiquitination.
   
  
 0.653
CG2926
Uncharacterized protein, isoform A; Zinc ion binding. It is involved in the biological process described with: regulation of alternative mRNA splicing, via spliceosome.
      
 0.627
mei-W68
Meiotic W68 (mei-W68) encodes a protein thought to form a dimer with the TopoVIA subunit encoded by mei-P22 and is required for the formation of double strand breaks during meiosis.
   
 
 0.613
CG5767
DUF725 domain-containing protein.
      
 0.606
CG13947
Uncharacterized protein.
      
 0.530
CG12057
LP05863p.
      
 0.528
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.