Protein mesh; Required, together with Ssk and Tsp2A, for the proper organization of smooth septate junctions (sSJs), probably by mediating cell adhesion via its homophilic interaction. Also required for the correct subcellular localization of several sSJ components, such as Ssk, cora and l(2)gl, and for the barrier function of the midgut epithelium. Required for maintaining the three-layered structure of the proventriculus.

GEO07727p1.

Transcriptional coactivator yorkie; Transcriptional coactivator which is the critical downstream regulatory target in the Hippo/SWH (Sav/Wts/Hpo) signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein Hippo (Hpo), in complex with its regulatory protein Salvador (Sav), phosphorylates and activates Warts (Wts) in complex with its regulatory protein Mats, which in turn phosphorylates and inactivates the Yorkie (Yki) oncoprotein. The Hippo/ [...]

Uncharacterized protein, isoform B; ATP binding; protein serine/threonine kinase activity. It is involved in the biological process described with: peptidyl-threonine phosphorylation; peptidyl-serine phosphorylation; mesoderm development.

LP20791p; RNA binding; translation activator activity. It is involved in the biological process described with: regulation of translational initiation.

Protein anoxia up-regulated; Plays an important role in the regulation of tissue responsiveness to oxygen deprivation.

Fasciclin-3; Mediates cell adhesion in a Ca(2+)-independent manner. It plays a role in axon outgrowth, guidance and fasciculation of the developing nervous system.

IP12572p; Glycine-gated chloride ion channel activity; extracellular ligand-gated ion channel activity; GABA-A receptor activity; neurotransmitter receptor activity; Belongs to the ligand-gated ion channel (TC 1.A.9) family.