STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG7335PfkB domain-containing protein; Carbohydrate kinase activity; fructokinase activity; ketohexokinase activity. (372 aa)    
Predicted Functional Partners:
Hex-t2
Hexokinase type 2; Catalyzes the phosphorylation of various hexoses to hexose 6- phosphate.
   
 
 0.923
Ald2
Fructose-bisphosphate aldolase activity. It is involved in the biological process described with: fructose 1,6-bisphosphate metabolic process; glycolytic process.
   
 
 0.922
Hex-t1
Hexokinase type 1; Catalyzes the phosphorylation of various hexoses to hexose 6- phosphate.
   
 
 0.914
Sodh-1
Sorbitol dehydrogenase 1, isoform A; Zinc ion binding; L-iditol 2-dehydrogenase activity. It is involved in the biological process described with: oxidation-reduction process; sorbitol catabolic process.
   
 
 0.910
Sodh-2
Sorbitol dehydrogenase-2; L-iditol 2-dehydrogenase activity; zinc ion binding. It is involved in the biological process described with: oxidation-reduction process; sorbitol catabolic process.
   
 
 0.910
Ald1
Fructose-bisphosphate aldolase; May take part in developmental stage-specific or tissue -specific sugar-phosphate metabolisms. Protein acts on two substrates fructose 1,6-bisphosphate and fructose 1-phosphate (like other class I aldolases).
   
 
 0.905
Hex-A
Phosphotransferase; Hexokinase A (Hex-A) encodes a hexokinase involved in glucose homeostasis.
     
 0.904
Hex-C
Phosphotransferase; Hexokinase C (Hex-C) encodes a hexokinase involved in glucose homeostasis.
     
 0.904
Prps
Uncharacterized protein, isoform B; Magnesium ion binding; ATP binding; ribose phosphate diphosphokinase activity. It is involved in the biological process described with: ribonucleoside monophosphate biosynthetic process; purine nucleotide biosynthetic process; nucleoside metabolic process; nucleotide biosynthetic process; 5-phosphoribose 1-diphosphate biosynthetic process.
    
 
 0.542
Ate1
Arginyl-tRNA--protein transferase 1; Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. Does not arginylate cysteine residues (By similarity).
      
 0.475
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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