STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Experiments
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[Homology]
Score
Ir76bIonotropic receptor 76b (Ir76b) encodes a member of the Ionotropic Receptor (IR) family of variant ionotropic glutamate receptors. It functions in chemosensory detection of various amines and salt, as a probable co-receptor subunit. (636 aa)    
Predicted Functional Partners:
Ir64a
Ionotropic receptor 64a (Ir64a) encodes a member of the Ionotropic Receptor (IR) family of variant ionotropic glutamate receptors. It is part of a broad-specificity acid sensor that mediates avoidance behavior.
   
 
 0.945
Ir68a
Ionotropic glutamate receptor activity; ligand-gated ion channel activity. It is involved in the biological process described with: detection of chemical stimulus.
  
   
 0.934
Ir41a
Ionotropic receptor 41a; Ligand-gated ion channel activity. It is involved in the biological process described with: detection of chemical stimulus.
      
 0.916
Ir40a
Ionotropic receptor 40a; Integral part of a neural sensory system in the antenna that provides the neural basis for the response to environmental changes in humidity (hygrosensation). Together with Ir25a and Ir93a, mediates the response of the hygrosensory sacculus neurons to changes in relative humidity and is required for dry detection behavior. Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
      
 0.911
Ir75d
Ionotropic glutamate receptor activity; ligand-gated ion channel activity; signaling receptor activity. It is involved in the biological process described with: detection of chemical stimulus involved in sensory perception.
  
   
 0.902
Ir62a
Ionotropic receptor 62a; Ligand-gated ion channel activity. It is involved in the biological process described with: detection of chemical stimulus.
      
 0.899
Ir75a
Ionotropic receptor 75a; Odorant receptor for acetic and propionic acid. Functions as part of an olfactory receptor complex including the ionotropic receptor coreceptor Ir8a; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
  
   
 0.886
Ir84a
Ionotropic receptor 84a (Ir84a) encodes a member of the Ionotropic Receptor (IR) family of variant ionotropic glutamate receptors. It functions in detection of phenylacetic acid and controls male courtship behavior.
  
  
 0.880
Ir31a
Ionotropic glutamate receptor activity; ligand-gated ion channel activity. It is involved in the biological process described with: detection of chemical stimulus involved in sensory perception.
  
   
 0.868
Gr66a
Gustatory receptor for bitter taste 66a; Gustatory receptor required for response to the bitter in taste neurons. Gr66a cells respond to bitter compounds such as caffeine, theophylline, threonine or valine. Flies avoid bitter substances, suggesting that Gr66a neuron activity is sufficient to mediate avoidance behavior. Required for sensing and avoiding N,N- Diethyl-meta-toluamide (DEET), the most widely used insect repellent worldwide, as well as to L-canavanine, a plant-derived insecticide. Gr66a neurons are also involved in the sex-specific perception of molecules inducing male avoid [...]
   
  
 0.840
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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