| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Gdi | Rab39 | FBpp0311558 | FBpp0298273 | Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. | Rab39, isoform A; GTPase activity; protein binding; GTP binding. It is involved in the biological process described with: vesicle-mediated transport; Rab protein signal transduction; intracellular protein transport. | 0.805 |
| Gdi | Rab8 | FBpp0311558 | FBpp0074690 | Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. | Rab8, isoform A; Rab8 (Rab8) encodes a member of the Rab GTPase family that regulates the function of the recycling endosome, where it localizes. | 0.953 |
| Gdi | Rep | FBpp0311558 | FBpp0085658 | Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. | Rab proteins geranylgeranyltransferase component A; Binds unprenylated Rab proteins, presents it to the catalytic component B, and remains bound to it after the geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rab to a protein acceptor (By similarity). | 0.533 |
| Gdi | strat | FBpp0311558 | FBpp0079221 | Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. | Guanine nucleotide exchange factor MSS4 homolog; Guanine-nucleotide-releasing protein that acts on members of the sec4/ypt1/rab subfamily such as Rab8. During egg development, essential for establishing and maintaining epithelial cell polarity by regulating the correct polarized deposition of basal membrane (BM) proteins such as trol/Pcan and vkg/Coll IV to the basal surface of follicular epithelial (FE) cells. Likely to function by restricting the activity of the vesicle transport regulator Rab8 to the basal membrane, and thus directs BM protein-containing vesicles to the basal side o [...] | 0.716 |
| IFT20 | Rab8 | FBpp0289150 | FBpp0074690 | Intraflagellar transport 20; It is involved in the biological process described with: centrosome localization; intraciliary transport; cilium assembly; protein localization to cilium. | Rab8, isoform A; Rab8 (Rab8) encodes a member of the Rab GTPase family that regulates the function of the recycling endosome, where it localizes. | 0.868 |
| IFT20 | Sec10 | FBpp0289150 | FBpp0083932 | Intraflagellar transport 20; It is involved in the biological process described with: centrosome localization; intraciliary transport; cilium assembly; protein localization to cilium. | Exocyst complex component 5; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane; Belongs to the SEC10 family. | 0.810 |
| Rab39 | Gdi | FBpp0298273 | FBpp0311558 | Rab39, isoform A; GTPase activity; protein binding; GTP binding. It is involved in the biological process described with: vesicle-mediated transport; Rab protein signal transduction; intracellular protein transport. | Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. | 0.805 |
| Rab39 | Rab8 | FBpp0298273 | FBpp0074690 | Rab39, isoform A; GTPase activity; protein binding; GTP binding. It is involved in the biological process described with: vesicle-mediated transport; Rab protein signal transduction; intracellular protein transport. | Rab8, isoform A; Rab8 (Rab8) encodes a member of the Rab GTPase family that regulates the function of the recycling endosome, where it localizes. | 0.920 |
| Rab39 | Rep | FBpp0298273 | FBpp0085658 | Rab39, isoform A; GTPase activity; protein binding; GTP binding. It is involved in the biological process described with: vesicle-mediated transport; Rab protein signal transduction; intracellular protein transport. | Rab proteins geranylgeranyltransferase component A; Binds unprenylated Rab proteins, presents it to the catalytic component B, and remains bound to it after the geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rab to a protein acceptor (By similarity). | 0.760 |
| Rab8 | Gdi | FBpp0074690 | FBpp0311558 | Rab8, isoform A; Rab8 (Rab8) encodes a member of the Rab GTPase family that regulates the function of the recycling endosome, where it localizes. | Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. | 0.953 |
| Rab8 | IFT20 | FBpp0074690 | FBpp0289150 | Rab8, isoform A; Rab8 (Rab8) encodes a member of the Rab GTPase family that regulates the function of the recycling endosome, where it localizes. | Intraflagellar transport 20; It is involved in the biological process described with: centrosome localization; intraciliary transport; cilium assembly; protein localization to cilium. | 0.868 |
| Rab8 | Rab39 | FBpp0074690 | FBpp0298273 | Rab8, isoform A; Rab8 (Rab8) encodes a member of the Rab GTPase family that regulates the function of the recycling endosome, where it localizes. | Rab39, isoform A; GTPase activity; protein binding; GTP binding. It is involved in the biological process described with: vesicle-mediated transport; Rab protein signal transduction; intracellular protein transport. | 0.920 |
| Rab8 | Rep | FBpp0074690 | FBpp0085658 | Rab8, isoform A; Rab8 (Rab8) encodes a member of the Rab GTPase family that regulates the function of the recycling endosome, where it localizes. | Rab proteins geranylgeranyltransferase component A; Binds unprenylated Rab proteins, presents it to the catalytic component B, and remains bound to it after the geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rab to a protein acceptor (By similarity). | 0.850 |
| Rab8 | Sec10 | FBpp0074690 | FBpp0083932 | Rab8, isoform A; Rab8 (Rab8) encodes a member of the Rab GTPase family that regulates the function of the recycling endosome, where it localizes. | Exocyst complex component 5; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane; Belongs to the SEC10 family. | 0.877 |
| Rab8 | Sec15 | FBpp0074690 | FBpp0083436 | Rab8, isoform A; Rab8 (Rab8) encodes a member of the Rab GTPase family that regulates the function of the recycling endosome, where it localizes. | Exocyst complex component 6; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. | 0.911 |
| Rab8 | Sec3 | FBpp0074690 | FBpp0074993 | Rab8, isoform A; Rab8 (Rab8) encodes a member of the Rab GTPase family that regulates the function of the recycling endosome, where it localizes. | Exocyst complex component 1; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC3 family. | 0.822 |
| Rab8 | Sec6 | FBpp0074690 | FBpp0085888 | Rab8, isoform A; Rab8 (Rab8) encodes a member of the Rab GTPase family that regulates the function of the recycling endosome, where it localizes. | Exocyst complex component 3; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane; Belongs to the SEC6 family. | 0.833 |
| Rab8 | Sec8 | FBpp0074690 | FBpp0078326 | Rab8, isoform A; Rab8 (Rab8) encodes a member of the Rab GTPase family that regulates the function of the recycling endosome, where it localizes. | Exocyst complex component 4; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Involved in regulation of synaptic microtubule formation, and also regulation of synaptic growth and glutamate receptor trafficking. Does not appear to be required for basal neurotransmission. | 0.873 |
| Rab8 | strat | FBpp0074690 | FBpp0079221 | Rab8, isoform A; Rab8 (Rab8) encodes a member of the Rab GTPase family that regulates the function of the recycling endosome, where it localizes. | Guanine nucleotide exchange factor MSS4 homolog; Guanine-nucleotide-releasing protein that acts on members of the sec4/ypt1/rab subfamily such as Rab8. During egg development, essential for establishing and maintaining epithelial cell polarity by regulating the correct polarized deposition of basal membrane (BM) proteins such as trol/Pcan and vkg/Coll IV to the basal surface of follicular epithelial (FE) cells. Likely to function by restricting the activity of the vesicle transport regulator Rab8 to the basal membrane, and thus directs BM protein-containing vesicles to the basal side o [...] | 0.880 |
| Rep | Gdi | FBpp0085658 | FBpp0311558 | Rab proteins geranylgeranyltransferase component A; Binds unprenylated Rab proteins, presents it to the catalytic component B, and remains bound to it after the geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rab to a protein acceptor (By similarity). | Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. | 0.533 |