Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CG1461 | pip | FBpp0308581 | FBpp0074780 | Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. | Heparan sulfate 2-O-sulfotransferase pipe; Sulfotransferase involved in dorsoventral axis patterning in early embryos. Required for the specific ventral activation of a series of proteases acting in the perivitelline space between the embryonic membrane and the eggshell. Probably acts by mediating the sulfation of some glycoprotein or glycosaminoglycan stably deposited in the egg, whose ventrally localized modification leads to spatially restricted activation of the protease cascade. | 0.491 |
| CG5731 | CalpC | FBpp0079549 | FBpp0074005 | Alpha-galactosidase activity. It is involved in the biological process described with: oligosaccharide metabolic process; glycoside catabolic process; glycosylceramide catabolic process. | Calpain-C; Calpain C (CalpC) encodes one of four calcium-dependent cysteine proteases, but lack of conservation in the catalytic domain suggests it lacks proteolytic activity. | 0.461 |
| CG5731 | pip | FBpp0079549 | FBpp0074780 | Alpha-galactosidase activity. It is involved in the biological process described with: oligosaccharide metabolic process; glycoside catabolic process; glycosylceramide catabolic process. | Heparan sulfate 2-O-sulfotransferase pipe; Sulfotransferase involved in dorsoventral axis patterning in early embryos. Required for the specific ventral activation of a series of proteases acting in the perivitelline space between the embryonic membrane and the eggshell. Probably acts by mediating the sulfation of some glycoprotein or glycosaminoglycan stably deposited in the egg, whose ventrally localized modification leads to spatially restricted activation of the protease cascade. | 0.517 |
| CalpC | CG5731 | FBpp0074005 | FBpp0079549 | Calpain-C; Calpain C (CalpC) encodes one of four calcium-dependent cysteine proteases, but lack of conservation in the catalytic domain suggests it lacks proteolytic activity. | Alpha-galactosidase activity. It is involved in the biological process described with: oligosaccharide metabolic process; glycoside catabolic process; glycosylceramide catabolic process. | 0.461 |
| CalpC | Prx3 | FBpp0074005 | FBpp0082927 | Calpain-C; Calpain C (CalpC) encodes one of four calcium-dependent cysteine proteases, but lack of conservation in the catalytic domain suggests it lacks proteolytic activity. | Thioredoxin peroxidase 3; Peroxiredoxin 3 (Prx3) encodes an antioxidant protein involved in hydrogen peroxide catabolism and regulation of apoptosis. | 0.402 |
| CalpC | pip | FBpp0074005 | FBpp0074780 | Calpain-C; Calpain C (CalpC) encodes one of four calcium-dependent cysteine proteases, but lack of conservation in the catalytic domain suggests it lacks proteolytic activity. | Heparan sulfate 2-O-sulfotransferase pipe; Sulfotransferase involved in dorsoventral axis patterning in early embryos. Required for the specific ventral activation of a series of proteases acting in the perivitelline space between the embryonic membrane and the eggshell. Probably acts by mediating the sulfation of some glycoprotein or glycosaminoglycan stably deposited in the egg, whose ventrally localized modification leads to spatially restricted activation of the protease cascade. | 0.626 |
| Hsepi | pip | FBpp0085478 | FBpp0074780 | Heparan sulfate C5-epimerase (Hsepi) encodes a heparan sulfate modifying enzyme, which catalyzes the C5-epimerization of glucuronic acid, converting it to iduronic acid. Hsepi loss results in minor morphological defects and lifespan reduction. | Heparan sulfate 2-O-sulfotransferase pipe; Sulfotransferase involved in dorsoventral axis patterning in early embryos. Required for the specific ventral activation of a series of proteases acting in the perivitelline space between the embryonic membrane and the eggshell. Probably acts by mediating the sulfation of some glycoprotein or glycosaminoglycan stably deposited in the egg, whose ventrally localized modification leads to spatially restricted activation of the protease cascade. | 0.441 |
| Hsepi | sfl | FBpp0085478 | FBpp0076677 | Heparan sulfate C5-epimerase (Hsepi) encodes a heparan sulfate modifying enzyme, which catalyzes the C5-epimerization of glucuronic acid, converting it to iduronic acid. Hsepi loss results in minor morphological defects and lifespan reduction. | Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase; Essential bifunctional enzyme that catalyzes both the N- deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in diffusion of morphogen wingless (wg) via its role in heparan sulfate proteoglycans (HSPGs) biosynthesis, HSPGs being required for movement of wg morphogens. Required for wg signaling dur [...] | 0.976 |
| LanB2 | pip | FBpp0311281 | FBpp0074780 | Laminin B2 (LanB2) encodes a subunit of laminin, a heterotrimeric protein found in the extracellular matrix (ECM) and a major component of the basal lamina. Laminins interact with a variety of cell surface molecules such as integrin receptors and other secreted ECM components. It contributes to ECM organization, tissue adhesion, cell motility and developmental patterning. | Heparan sulfate 2-O-sulfotransferase pipe; Sulfotransferase involved in dorsoventral axis patterning in early embryos. Required for the specific ventral activation of a series of proteases acting in the perivitelline space between the embryonic membrane and the eggshell. Probably acts by mediating the sulfation of some glycoprotein or glycosaminoglycan stably deposited in the egg, whose ventrally localized modification leads to spatially restricted activation of the protease cascade. | 0.448 |
| Prx3 | CalpC | FBpp0082927 | FBpp0074005 | Thioredoxin peroxidase 3; Peroxiredoxin 3 (Prx3) encodes an antioxidant protein involved in hydrogen peroxide catabolism and regulation of apoptosis. | Calpain-C; Calpain C (CalpC) encodes one of four calcium-dependent cysteine proteases, but lack of conservation in the catalytic domain suggests it lacks proteolytic activity. | 0.402 |
| Prx3 | pip | FBpp0082927 | FBpp0074780 | Thioredoxin peroxidase 3; Peroxiredoxin 3 (Prx3) encodes an antioxidant protein involved in hydrogen peroxide catabolism and regulation of apoptosis. | Heparan sulfate 2-O-sulfotransferase pipe; Sulfotransferase involved in dorsoventral axis patterning in early embryos. Required for the specific ventral activation of a series of proteases acting in the perivitelline space between the embryonic membrane and the eggshell. Probably acts by mediating the sulfation of some glycoprotein or glycosaminoglycan stably deposited in the egg, whose ventrally localized modification leads to spatially restricted activation of the protease cascade. | 0.420 |
| St2 | pip | FBpp0311929 | FBpp0074780 | Sulfotransferase 2 (St2) encodes one out of 4 sulfotransferases that catalyze the sulfonation of many proteins, lipids and glycosaminoglycans. | Heparan sulfate 2-O-sulfotransferase pipe; Sulfotransferase involved in dorsoventral axis patterning in early embryos. Required for the specific ventral activation of a series of proteases acting in the perivitelline space between the embryonic membrane and the eggshell. Probably acts by mediating the sulfation of some glycoprotein or glycosaminoglycan stably deposited in the egg, whose ventrally localized modification leads to spatially restricted activation of the protease cascade. | 0.498 |
| kon | pip | FBpp0289570 | FBpp0074780 | Kon-tiki, isoform B; Kon-tiki (kon) (also known as perdido) encodes a single transmembrane protein required to initiate muscle-tendon attachment in a group of embryonic and adult body muscles. kon mutants are embryonic lethal with rounded ventral longitudinal muscles. It concentrates at muscle attachment sites and genetically interacts with integrins. | Heparan sulfate 2-O-sulfotransferase pipe; Sulfotransferase involved in dorsoventral axis patterning in early embryos. Required for the specific ventral activation of a series of proteases acting in the perivitelline space between the embryonic membrane and the eggshell. Probably acts by mediating the sulfation of some glycoprotein or glycosaminoglycan stably deposited in the egg, whose ventrally localized modification leads to spatially restricted activation of the protease cascade. | 0.415 |
| pip | CG1461 | FBpp0074780 | FBpp0308581 | Heparan sulfate 2-O-sulfotransferase pipe; Sulfotransferase involved in dorsoventral axis patterning in early embryos. Required for the specific ventral activation of a series of proteases acting in the perivitelline space between the embryonic membrane and the eggshell. Probably acts by mediating the sulfation of some glycoprotein or glycosaminoglycan stably deposited in the egg, whose ventrally localized modification leads to spatially restricted activation of the protease cascade. | Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. | 0.491 |
| pip | CG5731 | FBpp0074780 | FBpp0079549 | Heparan sulfate 2-O-sulfotransferase pipe; Sulfotransferase involved in dorsoventral axis patterning in early embryos. Required for the specific ventral activation of a series of proteases acting in the perivitelline space between the embryonic membrane and the eggshell. Probably acts by mediating the sulfation of some glycoprotein or glycosaminoglycan stably deposited in the egg, whose ventrally localized modification leads to spatially restricted activation of the protease cascade. | Alpha-galactosidase activity. It is involved in the biological process described with: oligosaccharide metabolic process; glycoside catabolic process; glycosylceramide catabolic process. | 0.517 |
| pip | CalpC | FBpp0074780 | FBpp0074005 | Heparan sulfate 2-O-sulfotransferase pipe; Sulfotransferase involved in dorsoventral axis patterning in early embryos. Required for the specific ventral activation of a series of proteases acting in the perivitelline space between the embryonic membrane and the eggshell. Probably acts by mediating the sulfation of some glycoprotein or glycosaminoglycan stably deposited in the egg, whose ventrally localized modification leads to spatially restricted activation of the protease cascade. | Calpain-C; Calpain C (CalpC) encodes one of four calcium-dependent cysteine proteases, but lack of conservation in the catalytic domain suggests it lacks proteolytic activity. | 0.626 |
| pip | Hsepi | FBpp0074780 | FBpp0085478 | Heparan sulfate 2-O-sulfotransferase pipe; Sulfotransferase involved in dorsoventral axis patterning in early embryos. Required for the specific ventral activation of a series of proteases acting in the perivitelline space between the embryonic membrane and the eggshell. Probably acts by mediating the sulfation of some glycoprotein or glycosaminoglycan stably deposited in the egg, whose ventrally localized modification leads to spatially restricted activation of the protease cascade. | Heparan sulfate C5-epimerase (Hsepi) encodes a heparan sulfate modifying enzyme, which catalyzes the C5-epimerization of glucuronic acid, converting it to iduronic acid. Hsepi loss results in minor morphological defects and lifespan reduction. | 0.441 |
| pip | LanB2 | FBpp0074780 | FBpp0311281 | Heparan sulfate 2-O-sulfotransferase pipe; Sulfotransferase involved in dorsoventral axis patterning in early embryos. Required for the specific ventral activation of a series of proteases acting in the perivitelline space between the embryonic membrane and the eggshell. Probably acts by mediating the sulfation of some glycoprotein or glycosaminoglycan stably deposited in the egg, whose ventrally localized modification leads to spatially restricted activation of the protease cascade. | Laminin B2 (LanB2) encodes a subunit of laminin, a heterotrimeric protein found in the extracellular matrix (ECM) and a major component of the basal lamina. Laminins interact with a variety of cell surface molecules such as integrin receptors and other secreted ECM components. It contributes to ECM organization, tissue adhesion, cell motility and developmental patterning. | 0.448 |
| pip | Prx3 | FBpp0074780 | FBpp0082927 | Heparan sulfate 2-O-sulfotransferase pipe; Sulfotransferase involved in dorsoventral axis patterning in early embryos. Required for the specific ventral activation of a series of proteases acting in the perivitelline space between the embryonic membrane and the eggshell. Probably acts by mediating the sulfation of some glycoprotein or glycosaminoglycan stably deposited in the egg, whose ventrally localized modification leads to spatially restricted activation of the protease cascade. | Thioredoxin peroxidase 3; Peroxiredoxin 3 (Prx3) encodes an antioxidant protein involved in hydrogen peroxide catabolism and regulation of apoptosis. | 0.420 |
| pip | St2 | FBpp0074780 | FBpp0311929 | Heparan sulfate 2-O-sulfotransferase pipe; Sulfotransferase involved in dorsoventral axis patterning in early embryos. Required for the specific ventral activation of a series of proteases acting in the perivitelline space between the embryonic membrane and the eggshell. Probably acts by mediating the sulfation of some glycoprotein or glycosaminoglycan stably deposited in the egg, whose ventrally localized modification leads to spatially restricted activation of the protease cascade. | Sulfotransferase 2 (St2) encodes one out of 4 sulfotransferases that catalyze the sulfonation of many proteins, lipids and glycosaminoglycans. | 0.498 |
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