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nesLysophospholipid acyltransferase 5; Acyltransferase which mediates the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) to phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine or PC) (LPCAT activity). May also catalyze the conversion of lysophosphatidylethanolamine (1-acyl-2-hydroxy-sn-glycero-3- phosphoethanolamine or LPE) to phosphatidylethanolamine (1,2-diacyl-sn- glycero-3-phosphoethanolamine or PE) (LPEAT activity), as well as the conversion of lysophosphatidylserine (1-acyl-2-hydroxy-sn-glycero-3- phospho-L-serine or LPS) to phosphatidylser [...] (497 aa)    
Predicted Functional Partners:
Pss
LD10327p; Phosphotransferase activity, for other substituted phosphate groups; L-serine-phosphatidylethanolamine phosphatidyltransferase activity. It is involved in the biological process described with: phosphatidylserine biosynthetic process.
   
 
 0.946
Pisd
Phosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.
   
 
 0.945
LPCAT
Lysophosphatidylcholine acyltransferase; Acetyltransferase which mediates the conversion of 1-acyl-sn- glycero-3-phosphocholine (LPC) into phosphatidylcholine (PC) (By similarity). Has a calcium-independent activity (By similarity). Displays a clear preference for saturated fatty acyl-CoAs, and 1- myristoyl or 1-palmitoyl LPC as acyl donors and acceptors, respectively (By similarity). Involved in the regulation of lipid droplet number and size.
   
 
 0.944
CG33116
FI05338p; Phosphotransferase activity, for other substituted phosphate groups; ethanolaminephosphotransferase activity. It is involved in the biological process described with: phosphatidylethanolamine biosynthetic process; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
   
 
 0.925
bbc
Bb in a boxcar, isoform B; Diacylglycerol cholinephosphotransferase activity; ethanolaminephosphotransferase activity; phosphotransferase activity, for other substituted phosphate groups. It is involved in the biological process described with: phosphatidylethanolamine biosynthetic process; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
   
 
 0.918
CG7149
GH11618p; Ethanolaminephosphotransferase activity; phosphotransferase activity, for other substituted phosphate groups. It is involved in the biological process described with: phosphatidylethanolamine biosynthetic process; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
   
 
 0.912
CG31683
BcDNA.GH02384; O-acyltransferase activity. It is involved in the biological process described with: lipid metabolic process.
   
 
 0.906
Pld
Phospholipase; Phosphatidylinositol binding; phospholipase D activity.
   
 
 0.905
Pld3
GM01519p; Catalytic activity.
   
 
 0.905
SMSr
Sphingomyelin synthase-related 1; Sphingomyelin synthases synthesize sphingolipids through transfer of a phosphatidyl head group on to the primary hydroxyl of ceramide. SAMD8 is an endoplasmic reticulum (ER) transferase that has no sphingomyelin synthase activity but can convert phosphatidylethanolamine (PE) and ceramide to ceramide phosphoethanolamine (CPE) albeit with low product yield. Appears to operate as a ceramide sensor to control ceramide homeostasis in the endoplasmic reticulum rather than a converter of ceramides. Seems to be critical for the integrity of the early secretory [...]
   
 
 0.904
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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