STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG6836Organic solute transporter alpha-like protein; Probable transporter; Belongs to the OST-alpha family. (328 aa)    
Predicted Functional Partners:
CG15309
Protein yippee-like CG15309; Belongs to the yippee family.
      
 0.835
mEFTu1
Elongation factor Tu; Mitochondrial translation elongation factor Tu 1 (mEFTu1) encodes a protein predicted to function within mitochondria to bring aminoacyl-tRNA to the ribosome during the elongation phase of mRNA translation.
      
 0.626
Pis
CDP-diacylglycerol--inositol 3-phosphatidyltransferase; Catalyzes the biosynthesis of phosphatidylinositol (PtdIns) as well as PtdIns:inositol exchange reaction. May thus act to reduce an excessive cellular PtdIns content (By similarity). The exchange activity is due to the reverse reaction of PtdIns synthase and is dependent on CMP, which is tightly bound to the enzyme (By similarity). Required for the regeneration of the signaling molecule phosphatidylinositol 4,5- bisphosphate (PtdInsP2) from phosphatidic acid (PA) and maintenance of its steady supply during signaling, thus playing [...]
   
  
 0.605
Atg8a
Autophagy-related 8a (Atg8a) encodes a ubiquitin-like protein that is conjugated to phosphatidylethanolamine, and this lipid modification anchors it into the membrane of forming and completed autophagosomes. Atg8a product has roles in autophagosome formation, maintaining neuromuscular function and normal lifespan.
    
   0.544
Atg8b
Autophagy-related 8b, isoform A; Microtubule binding; protein tag; ubiquitin protein ligase binding; GABA receptor binding. It is involved in the biological process described with: macroautophagy; autophagosome maturation; cellular response to nitrogen starvation; autophagy of mitochondrion; autophagosome assembly.
    
   0.544
UQCR-C2
Endopeptidase activity; metal ion binding; ubiquinol-cytochrome-c reductase activity. It is involved in the biological process described with: mitochondrial electron transport, ubiquinol to cytochrome c; protein processing involved in protein targeting to mitochondrion.
      
 0.495
Lnk
Lnk, isoform D; Lnk (Lnk) encodes a member of the SH2B family of adaptor proteins. It functions within the insulin signalling pathway as an intracellular adaptor for the insulin receptor. It stabilises the interaction between the activated insulin receptor and the insulin receptor substrate, which are encoded by InR and chico respectively.
      
 0.495
CG11035
LD38634p.
      
 0.493
CG10465
RE57120p; It is involved in the biological process described with: protein homooligomerization.
      
 0.489
CG8888
GH26015p; Estradiol 17-beta-dehydrogenase activity; testosterone dehydrogenase (NAD+) activity.
   
  
 0.472
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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