Scheggia, isoform A; Scheggia (sea) encodes a carrier protein of the inner mitochondrial membrane that plays a central role in fatty acid and sterol biosynthesis. It catalyses an electroneutral exchange of citrate for another tricarboxylate, a dicarboxylate (L-malate), or phosphoenolpyruvate across the inner mitochondrial membrane. The product of sea is also required to prevent chromosome breaks.

Frataxin homolog, mitochondrial; Promotes the biosynthesis of heme as well as the assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+). May be able to store large amounts of the metal in the form of a ferrihydrite mineral by oligomerization. Required for ecdysteroidogenesis in the prothoracic gland which is necessary for larval to pupal transition. Belongs to the frataxin family.

Cysteine desulfurase, mitochondrial; Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron-sulfur (Fe- S) clusters; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

Cytochrome c heme lyase; Links covalently the heme group to the apoprotein of cytochrome c.

MICOS complex subunit Mic60; Mitofilin (Mitofilin) encodes a major component of the mitochondrial contact site (MICOS) complex, which is located at the mitochondrial crista junctions. It maintains crista structure and contact sites, and regulates mitochondrial motility. Mitofilin product functions downstream of the kinase encoded by Pink1, to maintain mitochondrial structure and cellular homeostasis.

Multi-substrate lipid kinase (Mulk) encodes a ceramide kinase involved in ceramide metabolism and pole cell migration.

RE54691p; Oxidoreductase activity, acting on the CH-CH group of donors; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor. It is involved in the biological process described with: oxidation-reduction process; heme A biosynthetic process.

Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.