STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cyp12c1Probable cytochrome P450 12c1, mitochondrial; Heme binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; iron ion binding. It is involved in the biological process described with: oxidation-reduction process; Belongs to the cytochrome P450 family. (524 aa)    
Predicted Functional Partners:
Cyp9f3
Cyp9f3; Heme binding; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; monooxygenase activity. It is involved in the biological process described with: oxidation-reduction process.
  
 
 0.668
Cyt-b5-r
Cytochrome b5-related protein; May play a role in muscle cell metabolism.
  
  
 0.559
CG3841
Carboxylic ester hydrolase activity; Belongs to the type-B carboxylesterase/lipase family.
   
  
 0.533
Pgant6
N-acetylgalactosaminyltransferase 6; Glycopeptide transferase involved in O-linked oligosaccharide biosynthesis, which catalyzes the transfer of an N-acetyl-D- galactosamine residue to an already glycosylated peptide. In contrast to other proteins of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on the protein receptor, but instead requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties. Some peptide transferase activity is however not excluded, considering that its appropriate peptide s [...]
      
 0.515
Cyp6d4
Probable cytochrome P450 6d4; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
  
 
0.506
Cyp6a13
Probable cytochrome P450 6a13; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
  
 
0.505
l(2)01289
Lethal (2) 01289, isoform F; It is involved in the biological process described with: cell redox homeostasis.
      
 0.495
Cyp6a23
Probable cytochrome P450 6a23; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
  
 
0.492
Cyp4d8
Cytochrome P450 4d8; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
  
  
0.468
Cyp313a4
Probable cytochrome P450 313a4; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
  
   
0.466
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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