STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TrpRS-mTryptophanyl-tRNA synthetase, mitochondrial (TrpRS-m) encodes a protein predicted to function within mitochondria to catalyze the ligation of tryptophan to its cognate tRNA to form tryptophanyl-tRNA. (665 aa)    
Predicted Functional Partners:
TrpRS
Tryptophanyl-tRNA synthetase (TrpRS) is expressed to high levels in the salivary gland. This could be incidental due to proximity to the salivary gland transcription factor encoded by sage; Belongs to the class-I aminoacyl-tRNA synthetase family.
     
 0.968
ArgRS-m
Arginyl-tRNA synthetase, mitochondrial, isoform A; ATP binding; arginine-tRNA ligase activity. It is involved in the biological process described with: arginyl-tRNA aminoacylation; mitochondrial translation; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 0.959
TyrRS
tRNA binding; tyrosine-tRNA ligase activity; ATP binding. It is involved in the biological process described with: tyrosyl-tRNA aminoacylation.
  
 
 0.936
ArgRS
Probable arginine--tRNA ligase, cytoplasmic; Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis.
  
  
 0.917
HisRS
Histidyl-tRNA synthetase, isoform D; histidine-tRNA ligase activity; ATP binding. It is involved in the biological process described with: histidyl-tRNA aminoacylation; mitochondrial translation.
  
 
 0.896
TyrRS-m
Tyrosine--tRNA ligase, mitochondrial; Tyrosyl-tRNA synthetase, mitochondrial (TyrRS-m) encodes an enzyme that catalyzes the ligation of tyrosine to the mitochondrial-encoded tRNA-Tyr. The TyrRS-m protein is encoded by a nuclear gene and imported to the mitochondria where it functions in mitochondrial protein synthesis; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 0.895
MetRS-m
Methionine--tRNA ligase, mitochondrial; ATP binding; methionine-tRNA ligase activity. It is involved in the biological process described with: methionyl-tRNA aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.895
CG4716
GH06388p; Methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity.
      
 0.894
SerRS-m
Seryl-tRNA synthetase, mitochondrial (SerRS-m) encodes an enzyme that catalyses the aminoacylation of tRNAser with serine, to be used for gene translation during protein synthesis.
  
  
 0.891
LeuRS-m
Leucyl-tRNA synthetase, mitochondrial; aminoacyl-tRNA editing activity; leucine-tRNA ligase activity; ATP binding. It is involved in the biological process described with: leucyl-tRNA aminoacylation; mitochondrial translation; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.888
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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