node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG42258 | Tsp74F | FBpp0288833 | FBpp0074921 | Uncharacterized protein, isoform C. | Tetraspanin 74F (Tsp74F) encodes encodes a tetraspanin, which spans the membrane four times. When the products of both Tsp74F and Tsp66E are removed, this results in defects in actin polarization, endocytosis, and distribution of the integrin subunit encoded by if during oogenesis. | 0.528 |
Dim1 | Tsp66E | FBpp0077125 | FBpp0076235 | Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. | Tetraspanin 66E (Tsp66E) encodes a tetraspanin, which spans the membrane four times. When the products of both Tsp66E and Tsp74F are removed, this results in defects in actin polarization, endocytosis, and distribution of the integrin subunit encoded by if during oogenesis. | 0.428 |
Dim1 | Tsp74F | FBpp0077125 | FBpp0074921 | Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. | Tetraspanin 74F (Tsp74F) encodes encodes a tetraspanin, which spans the membrane four times. When the products of both Tsp74F and Tsp66E are removed, this results in defects in actin polarization, endocytosis, and distribution of the integrin subunit encoded by if during oogenesis. | 0.434 |
Mp | Tsp74F | FBpp0301686 | FBpp0074921 | Multiplexin, isoform R; Multiplexin (Mp) encodes a Collagen XV/XVIII type protein that functions in motor axon pathfinding. It is required for normal calcium channel abundance, presynaptic calcium influx, and neurotransmitter release. | Tetraspanin 74F (Tsp74F) encodes encodes a tetraspanin, which spans the membrane four times. When the products of both Tsp74F and Tsp66E are removed, this results in defects in actin polarization, endocytosis, and distribution of the integrin subunit encoded by if during oogenesis. | 0.407 |
Prestin | Tsp74F | FBpp0074919 | FBpp0074921 | FI18412p1; It is involved in the biological process described with: formate transport; sulfate transport; bicarbonate transport; oxalate transport; calcium ion transmembrane transport. | Tetraspanin 74F (Tsp74F) encodes encodes a tetraspanin, which spans the membrane four times. When the products of both Tsp74F and Tsp66E are removed, this results in defects in actin polarization, endocytosis, and distribution of the integrin subunit encoded by if during oogenesis. | 0.805 |
Prestin | Wdr92 | FBpp0074919 | FBpp0074910 | FI18412p1; It is involved in the biological process described with: formate transport; sulfate transport; bicarbonate transport; oxalate transport; calcium ion transmembrane transport. | WD repeat domain 92; Protein domain specific binding; ubiquitin binding. It is involved in the biological process described with: positive regulation of transcription by RNA polymerase II; calcineurin-NFAT signaling cascade. | 0.405 |
Prestin | tilB | FBpp0074919 | FBpp0077037 | FI18412p1; It is involved in the biological process described with: formate transport; sulfate transport; bicarbonate transport; oxalate transport; calcium ion transmembrane transport. | Protein tilB; Touch insensitive larva B (tilB) encodes a protein required for the assembly and/or transport to the cilium of axonemal dynein arms. tilB depletion results in deafness and male sterility because it specifically affects chordotonal neurons and spermatids, the only fly motile cilia cells. It interacts with the product of Zmynd10, which has a similar distribution and mutant phenotype. | 0.497 |
TSG101 | Tsp66E | FBpp0075088 | FBpp0076235 | Tumor susceptibility gene 101 (TSG101) encodes an ESCRT-I complex component that acts as an adapter for membrane rearrangements operated by ESCRT-III. Its roles include endosomal sorting of ubiquitinated cargoes, which is important for signaling regulation, cytokinesis, and budding of viruses and exovesicles. | Tetraspanin 66E (Tsp66E) encodes a tetraspanin, which spans the membrane four times. When the products of both Tsp66E and Tsp74F are removed, this results in defects in actin polarization, endocytosis, and distribution of the integrin subunit encoded by if during oogenesis. | 0.563 |
TSG101 | Tsp74F | FBpp0075088 | FBpp0074921 | Tumor susceptibility gene 101 (TSG101) encodes an ESCRT-I complex component that acts as an adapter for membrane rearrangements operated by ESCRT-III. Its roles include endosomal sorting of ubiquitinated cargoes, which is important for signaling regulation, cytokinesis, and budding of viruses and exovesicles. | Tetraspanin 74F (Tsp74F) encodes encodes a tetraspanin, which spans the membrane four times. When the products of both Tsp74F and Tsp66E are removed, this results in defects in actin polarization, endocytosis, and distribution of the integrin subunit encoded by if during oogenesis. | 0.407 |
TSG101 | Tsp96F | FBpp0075088 | FBpp0303196 | Tumor susceptibility gene 101 (TSG101) encodes an ESCRT-I complex component that acts as an adapter for membrane rearrangements operated by ESCRT-III. Its roles include endosomal sorting of ubiquitinated cargoes, which is important for signaling regulation, cytokinesis, and budding of viruses and exovesicles. | Tetraspanin. | 0.650 |
Tsp66E | Dim1 | FBpp0076235 | FBpp0077125 | Tetraspanin 66E (Tsp66E) encodes a tetraspanin, which spans the membrane four times. When the products of both Tsp66E and Tsp74F are removed, this results in defects in actin polarization, endocytosis, and distribution of the integrin subunit encoded by if during oogenesis. | Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. | 0.428 |
Tsp66E | TSG101 | FBpp0076235 | FBpp0075088 | Tetraspanin 66E (Tsp66E) encodes a tetraspanin, which spans the membrane four times. When the products of both Tsp66E and Tsp74F are removed, this results in defects in actin polarization, endocytosis, and distribution of the integrin subunit encoded by if during oogenesis. | Tumor susceptibility gene 101 (TSG101) encodes an ESCRT-I complex component that acts as an adapter for membrane rearrangements operated by ESCRT-III. Its roles include endosomal sorting of ubiquitinated cargoes, which is important for signaling regulation, cytokinesis, and budding of viruses and exovesicles. | 0.563 |
Tsp66E | Tsp74F | FBpp0076235 | FBpp0074921 | Tetraspanin 66E (Tsp66E) encodes a tetraspanin, which spans the membrane four times. When the products of both Tsp66E and Tsp74F are removed, this results in defects in actin polarization, endocytosis, and distribution of the integrin subunit encoded by if during oogenesis. | Tetraspanin 74F (Tsp74F) encodes encodes a tetraspanin, which spans the membrane four times. When the products of both Tsp74F and Tsp66E are removed, this results in defects in actin polarization, endocytosis, and distribution of the integrin subunit encoded by if during oogenesis. | 0.504 |
Tsp66E | mol | FBpp0076235 | FBpp0110314 | Tetraspanin 66E (Tsp66E) encodes a tetraspanin, which spans the membrane four times. When the products of both Tsp66E and Tsp74F are removed, this results in defects in actin polarization, endocytosis, and distribution of the integrin subunit encoded by if during oogenesis. | Moladietz, isoform A; Protein binding. It is involved in the biological process described with: protein localization; protein transport; long-term memory; response to oxidative stress. | 0.414 |
Tsp74F | CG42258 | FBpp0074921 | FBpp0288833 | Tetraspanin 74F (Tsp74F) encodes encodes a tetraspanin, which spans the membrane four times. When the products of both Tsp74F and Tsp66E are removed, this results in defects in actin polarization, endocytosis, and distribution of the integrin subunit encoded by if during oogenesis. | Uncharacterized protein, isoform C. | 0.528 |
Tsp74F | Dim1 | FBpp0074921 | FBpp0077125 | Tetraspanin 74F (Tsp74F) encodes encodes a tetraspanin, which spans the membrane four times. When the products of both Tsp74F and Tsp66E are removed, this results in defects in actin polarization, endocytosis, and distribution of the integrin subunit encoded by if during oogenesis. | Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. | 0.434 |
Tsp74F | Mp | FBpp0074921 | FBpp0301686 | Tetraspanin 74F (Tsp74F) encodes encodes a tetraspanin, which spans the membrane four times. When the products of both Tsp74F and Tsp66E are removed, this results in defects in actin polarization, endocytosis, and distribution of the integrin subunit encoded by if during oogenesis. | Multiplexin, isoform R; Multiplexin (Mp) encodes a Collagen XV/XVIII type protein that functions in motor axon pathfinding. It is required for normal calcium channel abundance, presynaptic calcium influx, and neurotransmitter release. | 0.407 |
Tsp74F | Prestin | FBpp0074921 | FBpp0074919 | Tetraspanin 74F (Tsp74F) encodes encodes a tetraspanin, which spans the membrane four times. When the products of both Tsp74F and Tsp66E are removed, this results in defects in actin polarization, endocytosis, and distribution of the integrin subunit encoded by if during oogenesis. | FI18412p1; It is involved in the biological process described with: formate transport; sulfate transport; bicarbonate transport; oxalate transport; calcium ion transmembrane transport. | 0.805 |
Tsp74F | TSG101 | FBpp0074921 | FBpp0075088 | Tetraspanin 74F (Tsp74F) encodes encodes a tetraspanin, which spans the membrane four times. When the products of both Tsp74F and Tsp66E are removed, this results in defects in actin polarization, endocytosis, and distribution of the integrin subunit encoded by if during oogenesis. | Tumor susceptibility gene 101 (TSG101) encodes an ESCRT-I complex component that acts as an adapter for membrane rearrangements operated by ESCRT-III. Its roles include endosomal sorting of ubiquitinated cargoes, which is important for signaling regulation, cytokinesis, and budding of viruses and exovesicles. | 0.407 |
Tsp74F | Tsp66E | FBpp0074921 | FBpp0076235 | Tetraspanin 74F (Tsp74F) encodes encodes a tetraspanin, which spans the membrane four times. When the products of both Tsp74F and Tsp66E are removed, this results in defects in actin polarization, endocytosis, and distribution of the integrin subunit encoded by if during oogenesis. | Tetraspanin 66E (Tsp66E) encodes a tetraspanin, which spans the membrane four times. When the products of both Tsp66E and Tsp74F are removed, this results in defects in actin polarization, endocytosis, and distribution of the integrin subunit encoded by if during oogenesis. | 0.504 |