STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Oatp74DSolute carrier organic anion transporter family member 74D; Transporter that mediates the cellular uptake of ecdysteroids, including ecdysone, from the hemolymph. Belongs to the organo anion transporter (TC 2.A.60) family. (819 aa)    
Predicted Functional Partners:
EcR
Ecdysone receptor (EcR) encodes a protein that interacts with the product of usp to form the nuclear ecdysone receptor heterodimer, which modulates, in conjunction with co-activators and co-repressors, the activities of hundreds of genes in a tissue- and stage-specific way. EcR is widely expressed in embryonic and larval tissues and in some adult tissues where its activities (modulated by the hormone ecdysone) trigger both molting and metamorphosis.
   
  
 0.608
CG13384
Uncharacterized protein, isoform C; Amino acid transmembrane transporter activity. It is involved in the biological process described with: amino acid transmembrane transport.
      
 0.601
ImpE3
Ecdysone-inducible gene E3; It is involved in the biological process described with: imaginal disc eversion.
      
 0.533
CG10939
GH04176p; CG10939 encodes a protein that functions as a scaffold linking the plasma membrane and cytoskeletal linker proteins encoded by Mer and Moe. Via interaction with the products of Slik and flw, it regulates the activity of the products of Mer and Moe in epithelial cell adhesion.
    
 
 0.528
CG15646
Uncharacterized protein, isoform A.
      
 0.497
plum
Plum, isoform B; Plum (plum) encodes an Ig-superfamily transmembrane protein. It is required for developmental pruning of both mushroom body neurons and motor neurons via TGF-beta signaling. plum genetically interacts with myo and babo.
      
 0.497
CG4630
Uncharacterized protein, isoform B; Transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport.
   
  
 0.496
senju
UDP-galactose transporter senju; UDP-galactose transporter involved in the synthesis of galactose-containing glycans. Plays a role in quiescence of the innate immune response, possibly by regulating glycosylation of the Toll pathway ligand spz.
      
 0.495
CG33156
Uncharacterized protein, isoform E; NAD+ kinase activity. It is involved in the biological process described with: NAD metabolic process; NADP biosynthetic process.
      
 0.489
SP1173
SP1173, isoform A.
   
  
 0.475
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.