Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CG6034Amino_oxidase domain-containing protein; Polyamine oxidase activity; oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process. (479 aa)    
Predicted Functional Partners:
CG6123
GH13094p.
      
 0.779
CG8768
GH17516p; Coenzyme binding; catalytic activity.
      
 0.743
CG42540
Band 7 protein CG42540.
      
 0.654
CG10089
Uncharacterized protein, isoform E; Protein tyrosine/serine/threonine phosphatase activity. It is involved in the biological process described with: protein dephosphorylation.
      
 0.644
alph
Alphabet, isoform E; Alphabet (alph) encodes a Ser/Thr phosphatase that regulates RAS/MAPK signaling.
      
 0.598
klg
LD10776p; Klingon (klg) encodes a homophilic cell adhesion molecule that is regulated by Notch signalling. It is involved in long term memory formation and photoreceptor cell commitment.
      
 0.597
tinc
Tincar (tinc) encodes a transmembrane protein involved in the regulation of the development of ommatidial cells. tinc mRNA expression is negatively regulated by the product of svp in a cardioblast subpopulation.
      
 0.597
Lar
Tyrosine-protein phosphatase Lar; Possible cell adhesion receptor (Probable). It possesses an intrinsic protein tyrosine phosphatase activity (PTPase). It controls motor axon guidance. In the developing eye, has a role in normal axonal targeting of the R7 photoreceptor, where it negatively regulates bdl. Inhibits bdl cell adhesion activity in vitro; this effect is independent of its PTPase function.
      
 0.513
gol
Goliath (gol) encodes an E3 ubiquitin ligase, whose cellular substrates are unknown. During embyrogenesis gol is expressed in fusion-competence myoblasts of the somatic and visceral mesoderm.
      
 0.449
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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