Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CG7692Uncharacterized protein, isoform A. (1324 aa)    
Predicted Functional Partners:
tea
Protein telomere ends associated; Protects telomeres from fusion. Likely to function as a component of the MTV complex along with moi and ver. The complex binds single-stranded DNA in a sequence-independent manner and can protect it from DNA degradation.
   
  
 0.809
CG1815
GH01331p; Methylated histone binding; lysine-acetylated histone binding. It is involved in the biological process described with: regulation of transcription, DNA-templated.
   
  
 0.758
CG1737
FI19420p1.
   
  
 0.754
CG30403
Uncharacterized protein; DNA binding.
      
 0.741
Rrp6
Rrp6, isoform B; Rrp6 (Rrp6) encodes an exoribonuclease that forms part of the RNA processing exosome complex. It is involved in the regulation of cell cycle progresion and mRNA surveillance.
   
   0.678
mkg-p
Monkey king protein, isoform A; RNA uridylyltransferase activity; nucleotidyltransferase activity. It is involved in the biological process described with: mRNA processing; pre-miRNA processing; RNA 3' uridylation.
   
  
 0.655
vers
Versatile (vers) encodes a component of the heterochromatin protein 1 complex that regulates adult testis germline stem cell fate.
   
  
 0.651
Eps-15
Epidermal growth factor receptor pathway substrate clone 15 (Eps-15) encodes a multi-domain adaptor protein involved in endocytosis. It interacts with several other endocytic factors such as those encoded by shi, stnB, Dap160 and AP-2alpha. It is enriched at sites of endocytosis and is required for normal synaptic bouton development and vesicle endocytosis during high frequency stimulation.
   
   0.635
HIPP1
HP1 and insulator partner protein 1 (HIPP1) encodes a chromatin-associated protein, displaying strong protein-protein interaction with the product of Su(var)205. It is localized to pericentric heterochromatin, and potentially has a separate role bound to insulators along with the products of su(Hw), mod(mdg4) and Cp190.
   
 
 0.625
sov
Small ovary, isoform A; Nucleic acid binding.
   
 
 0.617
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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