STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
QIL1MICOS complex subunit MIC13 homolog QIL1; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (122 aa)    
Predicted Functional Partners:
CG5903
MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
   
 0.944
Chchd3
Coiled-coil-helix-coiled-coil-helix domain containing 3 (Chchd3) encodes a mitochondrial inner membrane protein that is required for mitochondrial fusion. Loss of Chchd3 leads to inactivation of Hippo activity, decreased tissue growth, cell proliferation defects, oxidative stress and JNK pathway activation.
   
 0.924
NP15.6
GEO04710p1; It is involved in the biological process described with: respiratory electron transport chain.
   
    0.775
ND-PDSW
NADH dehydrogenase (Ubiquinone) PDSW subunit, isoform A; NADH dehydrogenase activity. It is involved in the biological process described with: mitochondrial electron transport, NADH to ubiquinone.
   
    0.753
ND-B16.6
NADH dehydrogenase (ubiquinone) activity. It is involved in the biological process described with: mitochondrial electron transport, NADH to ubiquinone.
   
    0.728
ND-15
NADH dehydrogenase (Ubiquinone) 15 kDa subunit, isoform A; It is involved in the biological process described with: mitochondrial electron transport, NADH to ubiquinone.
   
    0.719
ND-19
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
   
    0.708
COX5B
Cytochrome-c oxidase activity. It is involved in the biological process described with: mitochondrial electron transport, cytochrome c to oxygen; mitochondrial ATP synthesis coupled proton transport.
   
    0.703
capt
Adenylyl cyclase-associated protein; Capulet (capt) encodes a conserved actin binding protein that functions across eukaryotes to negatively regulate actin filament assembly. Different types of actin filament formation are differentially affected by the loss of capt.
   
 
 0.678
ND-23
NADH dehydrogenase (Ubiquinone) 23 kDa subunit; NADH dehydrogenase activity; 4 iron, 4 sulfur cluster binding. It is involved in the biological process described with: aerobic respiration; mitochondrial ATP synthesis coupled electron transport; mitochondrial electron transport, NADH to ubiquinone; mitochondrial respiratory chain complex I assembly.
   
    0.673
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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