STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dbp73DProbable ATP-dependent RNA helicase Dbp73D; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits. (687 aa)    
Predicted Functional Partners:
CG5033
Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family.
   
 
 0.958
nop5
CG10206-PA; snoRNA binding. It is involved in the biological process described with: rRNA processing.
  
 
 0.923
CG3335
Uncharacterized protein; Helicase activity; mRNA binding; RNA binding. It is involved in the biological process described with: mRNA cis splicing, via spliceosome; regulation of alternative mRNA splicing, via spliceosome.
   
   0.917
CG12499
Uncharacterized protein; It is involved in the biological process described with: maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA).
   
 
 0.887
Hlc
Helicase, isoform A; ATP binding; RNA helicase activity; RNA binding.
  
 
0.844
pit
Probable ATP-dependent RNA helicase pitchoune; Probable RNA-dependent helicase. Functions in cell growth and proliferation. May have a role in ribosome biogenesis and, consequently, in protein biosynthesis.
  
  
0.841
CG13026
Uncharacterized protein, isoform B.
      
 0.839
CG6833
GH21710p; Nucleic acid binding; 3'-5' exonuclease activity; exonuclease activity. It is involved in the biological process described with: rRNA processing.
  
 
 0.827
ppan
Protein Peter pan; Required for initiation of larval growth and normal mitotic growth but is not absolutely required for general biosynthesis or DNA replication. Required for progression of normal oogenesis and maturation of some imaginal tissues into adult structures.
   
   0.825
Mat89Ba
Nucleolar protein 6; RNA binding. It is involved in the biological process described with: tRNA export from nucleus; rRNA processing; Belongs to the NRAP family.
   
 
 0.824
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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