STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
retininRetinin; Structural constituent of eye lens. (191 aa)    
Predicted Functional Partners:
Nplp3
Neuropeptide-like 3; Neuropeptide hormone activity. It is involved in the biological process described with: neuropeptide signaling pathway.
   
  
 0.901
Cpr72Ec
Cuticular protein 72Ec; Structural constituent of eye lens; structural constituent of chitin-based larval cuticle; structural constituent of cuticle. It is involved in the biological process described with: chitin-based cuticle development.
   
  
 0.621
Cpr66D
Cuticular protein 66D; Structural constituent of eye lens; structural constituent of chitin-based larval cuticle; structural constituent of cuticle. It is involved in the biological process described with: chitin-based cuticle development.
      
 0.603
Pdh
Photoreceptor dehydrogenase (Pdh) encodes a retinal pigment cell dehydrogenase involved in retinol metabolism; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
    0.586
Acyp
Acylphosphatase-1; Acylphosphatase activity.
      
 0.528
CG1561
CHK domain-containing protein.
   
    0.520
CG7214
HL02931p.
   
  
 0.510
CG9297
RE20510p; It is involved in the biological process described with: endocytosis; endosomal transport.
   
  
 0.507
Cyp313a1
Probable cytochrome P450 313a1; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
   
  
 0.487
CG10912
GH07575p; It is involved in the biological process described with: cold acclimation.
      
 0.468
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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