STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG4229LD44179p. (256 aa)    
Predicted Functional Partners:
CG9331
GH13879p; Hydroxypyruvate reductase activity; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; NAD binding; glyoxylate reductase (NADP) activity; glycerate dehydrogenase activity. It is involved in the biological process described with: oxidation-reduction process; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
      
 0.892
tzn
Tenzing norgay, isoform C; Hydroxyacylglutathione hydrolase activity. It is involved in the biological process described with: methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione; response to hypoxia.
      
 0.838
CG43759
Uncharacterized protein, isoform B.
      
 0.836
Tpst
Protein-tyrosine sulfotransferase; Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides (By similarity). Has a role in protein secretion; Belongs to the protein sulfotransferase family.
      
 0.793
CG3819
RE59221p; It is involved in the biological process described with: apoptotic DNA fragmentation; DNA catabolic process, endonucleolytic.
      
 0.700
plx
Pollux, isoform C; Pollux (plx) encodes a Rab GTPase activating protein involved in cell adhesion mediated by integrins.
      
 0.668
phu
Alkaline phosphatase activity. It is involved in the biological process described with: dephosphorylation; response to hypoxia; response to nicotine.
      
 0.629
CG14568
RE21944p.
   
    0.608
CG14573
Uncharacterized protein.
   
    0.570
shep
Alan shepard (shep) encodes an evolutionarily conserved RNA/DNA binding protein that regulates alternative splicing and gypsy insulator activities. It regulates neural development during the embryonic and larval stages, and neuronal remodeling during metamorphosis.
      
 0.547
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.