STRINGSTRING
Z600 protein (fruit fly) - STRING interaction network
Z600 is a mitotic inhibitor that binds to the hydrophobic patch of Cyclins. Z600 roles include the switch in cell cycle mode in blastoderm embryos, and delaying mitosis in the mesoderm anlage to avoid an interference of mitosis and morphogenesis in Drosophila melanogaster
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Z600Z600 is a mitotic inhibitor that binds to the hydrophobic patch of Cyclins. Z600 roles include the switch in cell cycle mode in blastoderm embryos, and delaying mitosis in the mesoderm anlage to avoid an interference of mitosis and morphogenesis (90 aa)    
Predicted Functional Partners:
CG34214
annotation not available (148 aa)
     
        0.881
Capr
Caprin is an RNA-binding translational regulator that is present in cytoplasmic RNA granules (neuronal granules and stress granules). It modulates diverse cellular processes including neuronal function, cell proliferation and differentiation through post-transcriptional regulation of target RNAs (961 aa)
           
  0.658
Cpr49Ad
Cuticular protein 49Ad; Structural constituent of chitin-based larval cuticle; structural constituent of chitin-based cuticle. It is involved in the biological process described with- chitin-based cuticle development (166 aa)
           
  0.655
halo
Halo (150 aa)
     
        0.598
SNCF
SoxNeuro Co-Factor; Protein binding. It is involved in the biological process described with- positive regulation of transcription from RNA polymerase II promoter; regulation of localization (146 aa)
     
        0.575
CycB
G2/mitotic-specific cyclin-B; Cyclin B (CycB) binds to Cdk1, thereby promoting Cdk1’s protein kinase activity. The complex CycB-Cdk1 complex induces the start of mitosis. During late metaphase of mitosis and continuing in G1, CycB is rapidly degraded (involving APC/C and the proteasome), resulting in inactivation of Cdk1 protein kinase activity, and allowing termination of mitosis (530 aa)
       
 
  0.517
CycE
G1/S-specific cyclin-E; Essential for the control of the cell cycle at the G1/S (start) transition. Targeted by archipelago for degradation by the SFC ubiquitin ligase complex (712 aa)
       
 
  0.500
BobA
Brother of bearded A; Protein binding. It is involved in the biological process described with- sensory organ precursor cell fate determination; cell fate specification; Notch signaling pathway; sensory organ development; defense response to bacterium (78 aa)
     
   
  0.486
Cdk1
Cyclin-dependent kinase (Cdk1) is a catalytic protein kinase subunit that can only become active after association with either CycA, CycB or CycB3. The protein kinase activities of these complexes (CycA-Cdk1, CycB-Cdk1, CycB3-Cdk1) control important aspects of progression through the cell cycle. Functionally, the different Cdk1 complexes are partially redundant. They phosphorylate hundreds of target proteins and are most important for progression into and through mitotic and meiotic M phases; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily (297 aa)
       
 
  0.486
Eip71CD
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (246 aa)
           
  0.483
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
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