| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CG10616 | CG16979 | FBpp0301023 | FBpp0075316 | Protein odr-4 homolog; May play a role in the trafficking of a subset of G-protein coupled receptors; Belongs to the ODR-4 family. | Probable Ufm1-specific protease 2; Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of UFM1, a ubiquitin-like modifier protein bound to a number of target proteins. Does not hydrolyze SUMO1 or ISG15 ubiquitin-like proteins. | 0.720 |
| CG11710 | CG16979 | FBpp0308739 | FBpp0075316 | Uncharacterized protein, isoform B; Transcription coactivator activity; zinc ion binding. It is involved in the biological process described with: positive regulation of transcription, DNA-templated. | Probable Ufm1-specific protease 2; Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of UFM1, a ubiquitin-like modifier protein bound to a number of target proteins. Does not hydrolyze SUMO1 or ISG15 ubiquitin-like proteins. | 0.532 |
| CG11710 | Ufl1 | FBpp0308739 | FBpp0081157 | Uncharacterized protein, isoform B; Transcription coactivator activity; zinc ion binding. It is involved in the biological process described with: positive regulation of transcription, DNA-templated. | E3 UFM1-protein ligase 1 homolog; E3 UFM1-protein ligase that mediates ufmylation of target proteins; Belongs to the UFL1 family. | 0.422 |
| CG11710 | Ufm1 | FBpp0308739 | FBpp0111299 | Uncharacterized protein, isoform B; Transcription coactivator activity; zinc ion binding. It is involved in the biological process described with: positive regulation of transcription, DNA-templated. | Ubiquitin-fold modifier 1; Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to substrate proteins as a monomer or a lysine- linked polymer (By similarity). The so-called ufmylation, requires the UFM1-activating E1 enzyme Uba5, the UFM1-conjugating E2 enzyme Ufc1, and the UFM1-ligase E3 enzyme Ufl1 (By similarity). This post- translational modification on lysine residues of proteins may play a crucial role in a number of cellular processes (By similarity). The Ufm1 cascade might play a role in the development of the neuromuscular junctions. | 0.408 |
| CG16979 | CG10616 | FBpp0075316 | FBpp0301023 | Probable Ufm1-specific protease 2; Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of UFM1, a ubiquitin-like modifier protein bound to a number of target proteins. Does not hydrolyze SUMO1 or ISG15 ubiquitin-like proteins. | Protein odr-4 homolog; May play a role in the trafficking of a subset of G-protein coupled receptors; Belongs to the ODR-4 family. | 0.720 |
| CG16979 | CG11710 | FBpp0075316 | FBpp0308739 | Probable Ufm1-specific protease 2; Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of UFM1, a ubiquitin-like modifier protein bound to a number of target proteins. Does not hydrolyze SUMO1 or ISG15 ubiquitin-like proteins. | Uncharacterized protein, isoform B; Transcription coactivator activity; zinc ion binding. It is involved in the biological process described with: positive regulation of transcription, DNA-templated. | 0.532 |
| CG16979 | CG30008 | FBpp0075316 | FBpp0087468 | Probable Ufm1-specific protease 2; Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of UFM1, a ubiquitin-like modifier protein bound to a number of target proteins. Does not hydrolyze SUMO1 or ISG15 ubiquitin-like proteins. | Elongation of very long chain fatty acids protein; Fatty acid elongase activity. | 0.543 |
| CG16979 | CG30291 | FBpp0075316 | FBpp0071478 | Probable Ufm1-specific protease 2; Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of UFM1, a ubiquitin-like modifier protein bound to a number of target proteins. Does not hydrolyze SUMO1 or ISG15 ubiquitin-like proteins. | CDK5RAP3-like protein; Probable regulator of cell proliferation. May regulate CDK5, NF-kappa-B-mediated gene transcription and p53/TP53 activation. Belongs to the CDK5RAP3 family. | 0.567 |
| CG16979 | CG5862 | FBpp0075316 | FBpp0083451 | Probable Ufm1-specific protease 2; Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of UFM1, a ubiquitin-like modifier protein bound to a number of target proteins. Does not hydrolyze SUMO1 or ISG15 ubiquitin-like proteins. | DDRGK domain-containing protein 1; Ubiquitin-like protein ligase binding. It is involved in the biological process described with: positive regulation of NF-kappaB transcription factor activity; Belongs to the DDRGK1 family. | 0.649 |
| CG16979 | CG9458 | FBpp0075316 | FBpp0081630 | Probable Ufm1-specific protease 2; Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of UFM1, a ubiquitin-like modifier protein bound to a number of target proteins. Does not hydrolyze SUMO1 or ISG15 ubiquitin-like proteins. | Elongation of very long chain fatty acids protein; Fatty acid elongase activity. | 0.533 |
| CG16979 | Uba5 | FBpp0075316 | FBpp0073354 | Probable Ufm1-specific protease 2; Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of UFM1, a ubiquitin-like modifier protein bound to a number of target proteins. Does not hydrolyze SUMO1 or ISG15 ubiquitin-like proteins. | Ubiquitin-like activating enzyme 5 (Uba5) encodes a member of the E1-like ubiquitin-activating enzyme family. It activates the protein encoded by Ufm1, and acts as a key factor in the ufmylation process. It is involved in ATP binding, catalytic activity, cofactor binding, metal ion binding, nucleotide binding and oxidoreductase activity. | 0.938 |
| CG16979 | Ufc1 | FBpp0075316 | FBpp0086402 | Probable Ufm1-specific protease 2; Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of UFM1, a ubiquitin-like modifier protein bound to a number of target proteins. Does not hydrolyze SUMO1 or ISG15 ubiquitin-like proteins. | Ubiquitin-fold modifier-conjugating enzyme 1; E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage (By similarity). As part of Ufm1 cascade, might play a role in the development of the neuromuscular junctions. | 0.955 |
| CG16979 | Ufl1 | FBpp0075316 | FBpp0081157 | Probable Ufm1-specific protease 2; Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of UFM1, a ubiquitin-like modifier protein bound to a number of target proteins. Does not hydrolyze SUMO1 or ISG15 ubiquitin-like proteins. | E3 UFM1-protein ligase 1 homolog; E3 UFM1-protein ligase that mediates ufmylation of target proteins; Belongs to the UFL1 family. | 0.943 |
| CG16979 | Ufm1 | FBpp0075316 | FBpp0111299 | Probable Ufm1-specific protease 2; Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of UFM1, a ubiquitin-like modifier protein bound to a number of target proteins. Does not hydrolyze SUMO1 or ISG15 ubiquitin-like proteins. | Ubiquitin-fold modifier 1; Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to substrate proteins as a monomer or a lysine- linked polymer (By similarity). The so-called ufmylation, requires the UFM1-activating E1 enzyme Uba5, the UFM1-conjugating E2 enzyme Ufc1, and the UFM1-ligase E3 enzyme Ufl1 (By similarity). This post- translational modification on lysine residues of proteins may play a crucial role in a number of cellular processes (By similarity). The Ufm1 cascade might play a role in the development of the neuromuscular junctions. | 0.992 |
| CG30008 | CG16979 | FBpp0087468 | FBpp0075316 | Elongation of very long chain fatty acids protein; Fatty acid elongase activity. | Probable Ufm1-specific protease 2; Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of UFM1, a ubiquitin-like modifier protein bound to a number of target proteins. Does not hydrolyze SUMO1 or ISG15 ubiquitin-like proteins. | 0.543 |
| CG30008 | CG9458 | FBpp0087468 | FBpp0081630 | Elongation of very long chain fatty acids protein; Fatty acid elongase activity. | Elongation of very long chain fatty acids protein; Fatty acid elongase activity. | 0.740 |
| CG30291 | CG16979 | FBpp0071478 | FBpp0075316 | CDK5RAP3-like protein; Probable regulator of cell proliferation. May regulate CDK5, NF-kappa-B-mediated gene transcription and p53/TP53 activation. Belongs to the CDK5RAP3 family. | Probable Ufm1-specific protease 2; Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of UFM1, a ubiquitin-like modifier protein bound to a number of target proteins. Does not hydrolyze SUMO1 or ISG15 ubiquitin-like proteins. | 0.567 |
| CG30291 | CG5862 | FBpp0071478 | FBpp0083451 | CDK5RAP3-like protein; Probable regulator of cell proliferation. May regulate CDK5, NF-kappa-B-mediated gene transcription and p53/TP53 activation. Belongs to the CDK5RAP3 family. | DDRGK domain-containing protein 1; Ubiquitin-like protein ligase binding. It is involved in the biological process described with: positive regulation of NF-kappaB transcription factor activity; Belongs to the DDRGK1 family. | 0.968 |
| CG30291 | Uba5 | FBpp0071478 | FBpp0073354 | CDK5RAP3-like protein; Probable regulator of cell proliferation. May regulate CDK5, NF-kappa-B-mediated gene transcription and p53/TP53 activation. Belongs to the CDK5RAP3 family. | Ubiquitin-like activating enzyme 5 (Uba5) encodes a member of the E1-like ubiquitin-activating enzyme family. It activates the protein encoded by Ufm1, and acts as a key factor in the ufmylation process. It is involved in ATP binding, catalytic activity, cofactor binding, metal ion binding, nucleotide binding and oxidoreductase activity. | 0.542 |
| CG30291 | Ufc1 | FBpp0071478 | FBpp0086402 | CDK5RAP3-like protein; Probable regulator of cell proliferation. May regulate CDK5, NF-kappa-B-mediated gene transcription and p53/TP53 activation. Belongs to the CDK5RAP3 family. | Ubiquitin-fold modifier-conjugating enzyme 1; E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage (By similarity). As part of Ufm1 cascade, might play a role in the development of the neuromuscular junctions. | 0.580 |