STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pgant8Polypeptide N-acetylgalactosaminyltransferase 8; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. It can both act as a peptide transferase that transfers GalNAc onto unmodified peptide substrates, and as a glycopeptide transferase that requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties. Prefers both EA2 and the diglycosylated Muc5AC-3/13 as substrates, albeit at very low levels fro Muc5AC-3/13. Belongs to the gl [...] (590 aa)    
Predicted Functional Partners:
CG6435
GEO10735p1; Lysozyme activity.
      
 0.839
Twdlbeta
Tweedlebeta; Structural constituent of chitin-based cuticle. It is involved in the biological process described with: chitin-based cuticle development; body morphogenesis.
   
  
 0.837
CG32054
Uncharacterized protein; Transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport.
      
 0.836
CG18258
IP12247p; Carboxylic ester hydrolase activity; lipase activity. It is involved in the biological process described with: lipid catabolic process.
      
 0.798
dany
Distal antenna-young (dany) encodes a chromatin-binding protein required in spermatocytes for a normal gene expression profile, meiosis and sperm production.
      
 0.795
CG5111
FI08017p; It is involved in the biological process described with: protein ubiquitination; regulation of ubiquitin-dependent protein catabolic process.
      
 0.795
CG2975
glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity; beta-1,3-galactosyltransferase activity. It is involved in the biological process described with: multicellular organism reproduction; protein glycosylation; O-glycan processing, core 1.
   
 
 0.670
AANATL3
Arylalkylamine N-acetyltransferase-like 3; N-acetyltransferase activity.
      
 0.670
otk2
Off-track2 (otk2) encodes a single-pass transmembrane protein with extracellular Ig-like repeats that functions as a coreceptor for the product of Wnt2.
      
 0.669
RpL22-like
Ribosomal protein L22-like (RpL22-like) encodes a eukaryotic-specific component of the large ribosomal subunit involved in protein synthesis.
      
 0.663
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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