STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Nplp2Neuropeptide-like 2; Neuropeptide hormone activity. It is involved in the biological process described with: defense response; neuropeptide signaling pathway; humoral immune response. (119 aa)    
Predicted Functional Partners:
Nplp4
Neuropeptide-like 4; Neuropeptide hormone activity. It is involved in the biological process described with: neuropeptide signaling pathway.
   
  
 0.796
Nplp3
Neuropeptide-like 3; Neuropeptide hormone activity. It is involved in the biological process described with: neuropeptide signaling pathway.
   
  
 0.794
IM33
Immune induced molecule 33 (IM33) encodes a protein that belongs to a class of small secreted peptides released in the hemolymph upon systemic microbial infection.
   
  
 0.621
CG1208
Uncharacterized protein, isoform C; Carbohydrate:proton symporter activity. It is involved in the biological process described with: glucose import; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
   
  
 0.604
CG13403
Uncharacterized protein, isoform A.
      
 0.600
CCHa1
Neuropeptide CCHamide-1; Ligand for the CCHamide-1 receptor CCHa1-R.
      
 0.548
Obp99c
Odorant-binding protein 99c, isoform A; Odorant binding. It is involved in the biological process described with: response to fungus; sensory perception of smell; sensory perception of chemical stimulus.
   
 
 0.532
Eglp4
Entomoglyceroporin 4, isoform F; Water channel activity; channel activity. It is involved in the biological process described with: transmembrane transport; renal system process; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
  
 0.526
CNMa
CNMamide, isoform B; CNMamide (CNMa) encodes a short signaling peptide that shows a potent agonist activity toward the G-protein coupled receptor encoded by CNMaR.
      
 0.523
CCHa2
Neuropeptide CCHamide-2; Ligand for the CCHamide-2 receptor CCHa2-R. In one study, shown to be an orexigenic peptide which induces appetite and stimulates food intake, leading to the release of insulin-like peptides which stimulate growth. In another study, shown to be a nutrient-sensitive peptide derived from peripheral tissues which controls growth by directly regulating the production and release of insulin-like peptides.
   
  
 0.515
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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