STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
caupHomeobox protein caupolican; Caupolican (caup) encodes a homeodomain-containing protein of the TALE subfamily and one of the three components of the Iroquois gene complex. caup product acts as a transcriptional regulator to control territorial and cell fate specification, cell sorting behaviour and pattern formation. It also plays a transcription independent cell-autonomous role in cell proliferation control. (693 aa)    
Predicted Functional Partners:
ara
Homeobox protein araucan; Araucan (ara) encodes a homeodomain-containing protein of the TALE subfamily and one of the three components of the Iroquois gene complex. ara product acts as a transcriptional regulator to control territorial and cell fate specification, cell sorting behaviour and pattern formation. It also plays a transcription independent cell-autonomous role in cell proliferation control.
  
  
0.786
slou
Homeobox protein slou; Slouch (slou) encodes a homeodomain transcription factor that is involved in the specification of a subset of somatic muscle progenitors and muscle founder cells; Belongs to the NK-1 homeobox family.
   
 
 0.714
Ptx1
Ptx1 (Ptx1) encodes a paired-like homeobox transcription factor expressed during embryogenesis and in the adult digestive tract. It is strongly expressed in the middle midgut (copper cell region) where it is required for local stem cell quiescence and proper function of this region.
   
  
 0.672
tup
Tailup, isoform A; Tailup (tup) encodes a transcription factor that regulates neuronal sub-type identity, including motor, serotonergic and dopaminergic neuron identity. It regulates germ band retraction, dorsal closure, muscle and heart development.
   
 
 0.614
CG4766
Protein mab-21-like; Belongs to the mab-21 family.
   
 
 0.610
salr
Spalt-related, isoform A; Spalt-related (salr) encodes a zinc finger transcriptional repressor that, together with the product of salm, mediates most dpp functions during development of the central part of the wing. It is repressed by the product of Ubx during haltere development.
   
  
 0.572
sowah
Sosondowah, isoform G.
   
  
 0.547
Abd-B
Homeobox protein abdominal-B; Abdominal B (Abd-B) is one of the three hox genes of the bithorax complex. The product of Abd-B specifies the identity of the posterior abdominal segments, the external genitalia and the gonads. It is also involved in regulating the post-mating-response.
   
 
 0.545
Dr
Muscle segmentation homeobox; Drop (Dr) encodes a homeodomain transcription factor involved in patterning of the neuroectoderm and wing disc, specification of myoblasts and neuroblasts, proper development of muscle, neuronal and glial cells, male genital disc, and regulation of glucose metabolism; Belongs to the Msh homeobox family.
   
 
 0.536
org-1
Optomotor-blind-related-gene-1, isoform A; Optomotor-blind-related-gene-1 (org-1) encodes a T-box transcription factor involved in the combinatorial activation of somatic muscle lineage-specific targets.
    
 
 0.527
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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