STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG10646RH33377p; It is involved in the biological process described with: protein ubiquitination. (383 aa)    
Predicted Functional Partners:
Vps51
Vacuolar protein sorting-associated protein 51 homolog; May act as a component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans- Golgi network (TGN); Belongs to the VPS51 family.
   
 
 0.912
Vps50
Vacuolar protein sorting 50; It is involved in the biological process described with: endocytic recycling; retrograde transport, endosome to Golgi.
   
 
 0.896
Vps53
Vacuolar protein sorting 53; It is involved in the biological process described with: retrograde transport, endosome to Golgi; endocytic recycling.
    
 
 0.890
scat
Vacuolar protein sorting-associated protein 54; May be involved in retrograde transport from early and late endosomes to late Golgi (By similarity). Required during spermatogenesis for sperm individualization; Belongs to the VPS54 family.
    
 
 0.885
Vps52
Vacuolar protein sorting 52; Rab GTPase binding; syntaxin binding. It is involved in the biological process described with: retrograde transport, endosome to Golgi; lysosomal transport; Golgi to vacuole transport; endocytic recycling.
    
 
 0.771
Golgin104
Golgin 104; Rab GTPase binding.
   
  
 0.649
thoc6
THO complex subunit 6; The THO complex is required for cell proliferation and for proper export of heat-shock mRNAs under heat stress. Belongs to the WD repeat THOC6 family.
   
 
 0.649
CG11583
Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family.
   
  
 0.551
CG11396
RE19263p; Endopeptidase activity. It is involved in the biological process described with: Golgi vesicle transport.
   
  
 0.534
Syx6
Syntaxin 6, isoform E; SNARE binding; SNAP receptor activity.
      
 0.532
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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