node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG6424 | Cdc42 | FBpp0086046 | FBpp0301153 | Uncharacterized protein, isoform A. | Cdc42 (Cdc42) encodes a GTPase signaling protein that acts as a molecular switch and functions as key regulator of the actin cytoskeleton. It plays a central role in diverse biological processes including actin cytoskeleton organization, mophogenesis, hemocyte migration, cell polarity, and wound repair. | 0.450 |
CG6424 | GEFmeso | FBpp0086046 | FBpp0289650 | Uncharacterized protein, isoform A. | Guanine nucleotide exchange factor in mesoderm (GEFmeso) encodes a protein that regulates the products of Rala and Cdc42. It is involved in leg morphogenesis and wing vein specification. | 0.495 |
CG6424 | Rac1 | FBpp0086046 | FBpp0304252 | Uncharacterized protein, isoform A. | Ras-related protein Rac1; During various developmental processes, regulates changes in cell morphology in response to extracellular signals. During oogenesis, mediates signaling from the tyrosine kinase (RTK) chemoattractant receptors (Egfr and Pvr) to the guidance pathway that control the directional persistent collective migration of the border cell (BC) cluster through the nurse cells to the oocyte. Once activating by Pvr and Egfr, promotes the formation of forward-directed actin protrusions which stabilize the DE- cadherin (shg)-mediated adhesions. In turn, DE-mediated adhesion bet [...] | 0.450 |
CG6424 | Rho1 | FBpp0086046 | FBpp0086354 | Uncharacterized protein, isoform A. | Ras-like GTP-binding protein Rho1; Has a role in regulating actin cytoskeletal organization: required during early development for proper execution of morphogenetic movements of individual cells and groups of cells important for the formation of the embryonic body plan. Plays a role in regulating dorsal closure during embryogenesis. During axis elongation, required for Rho-kinase Rok planar polarity and adherens junction localization as well as for generating a planar polarized distribution of the actin-binding protein Shrm. During embryogenesis, acts upstream of wash to regulate the d [...] | 0.450 |
CG6424 | RhoGAP68F | FBpp0086046 | FBpp0306217 | Uncharacterized protein, isoform A. | Rho GTPase activating protein at 68F (RhoGAP68F) encodes a GTPase activating protein acting upon small Rho-family GTPases involved in epithelial morphogenesis. It localizes to Rab4 recycling endosomes, forms a complex with the product of Rab4 and modulates the transport of Rab4 recycling endosomes back to the cell surface. | 0.705 |
CG6424 | RhoGAP71E | FBpp0086046 | FBpp0288504 | Uncharacterized protein, isoform A. | Rho GTPase activating protein at 71E (RhoGAP71E) encodes a Rho GTPase activating protein that is involved in the regulation of actin dynamics during epithelial morphogenesis. | 0.573 |
CG7083 | RhoGAP68F | FBpp0076331 | FBpp0306217 | UPF0183 protein CG7083; It is involved in the biological process described with: Golgi to plasma membrane protein transport; Belongs to the UPF0183 family. | Rho GTPase activating protein at 68F (RhoGAP68F) encodes a GTPase activating protein acting upon small Rho-family GTPases involved in epithelial morphogenesis. It localizes to Rab4 recycling endosomes, forms a complex with the product of Rab4 and modulates the transport of Rab4 recycling endosomes back to the cell surface. | 0.668 |
Cdc42 | CG6424 | FBpp0301153 | FBpp0086046 | Cdc42 (Cdc42) encodes a GTPase signaling protein that acts as a molecular switch and functions as key regulator of the actin cytoskeleton. It plays a central role in diverse biological processes including actin cytoskeleton organization, mophogenesis, hemocyte migration, cell polarity, and wound repair. | Uncharacterized protein, isoform A. | 0.450 |
Cdc42 | GEFmeso | FBpp0301153 | FBpp0289650 | Cdc42 (Cdc42) encodes a GTPase signaling protein that acts as a molecular switch and functions as key regulator of the actin cytoskeleton. It plays a central role in diverse biological processes including actin cytoskeleton organization, mophogenesis, hemocyte migration, cell polarity, and wound repair. | Guanine nucleotide exchange factor in mesoderm (GEFmeso) encodes a protein that regulates the products of Rala and Cdc42. It is involved in leg morphogenesis and wing vein specification. | 0.776 |
Cdc42 | Rac1 | FBpp0301153 | FBpp0304252 | Cdc42 (Cdc42) encodes a GTPase signaling protein that acts as a molecular switch and functions as key regulator of the actin cytoskeleton. It plays a central role in diverse biological processes including actin cytoskeleton organization, mophogenesis, hemocyte migration, cell polarity, and wound repair. | Ras-related protein Rac1; During various developmental processes, regulates changes in cell morphology in response to extracellular signals. During oogenesis, mediates signaling from the tyrosine kinase (RTK) chemoattractant receptors (Egfr and Pvr) to the guidance pathway that control the directional persistent collective migration of the border cell (BC) cluster through the nurse cells to the oocyte. Once activating by Pvr and Egfr, promotes the formation of forward-directed actin protrusions which stabilize the DE- cadherin (shg)-mediated adhesions. In turn, DE-mediated adhesion bet [...] | 0.763 |
Cdc42 | Rac2 | FBpp0301153 | FBpp0305023 | Cdc42 (Cdc42) encodes a GTPase signaling protein that acts as a molecular switch and functions as key regulator of the actin cytoskeleton. It plays a central role in diverse biological processes including actin cytoskeleton organization, mophogenesis, hemocyte migration, cell polarity, and wound repair. | Ras-related protein Rac2; Involved in integrin alpha-PS3/beta-nu-mediated phagocytosis of Gram-positive S.aureus by hemocytes. | 0.561 |
Cdc42 | Rho1 | FBpp0301153 | FBpp0086354 | Cdc42 (Cdc42) encodes a GTPase signaling protein that acts as a molecular switch and functions as key regulator of the actin cytoskeleton. It plays a central role in diverse biological processes including actin cytoskeleton organization, mophogenesis, hemocyte migration, cell polarity, and wound repair. | Ras-like GTP-binding protein Rho1; Has a role in regulating actin cytoskeletal organization: required during early development for proper execution of morphogenetic movements of individual cells and groups of cells important for the formation of the embryonic body plan. Plays a role in regulating dorsal closure during embryogenesis. During axis elongation, required for Rho-kinase Rok planar polarity and adherens junction localization as well as for generating a planar polarized distribution of the actin-binding protein Shrm. During embryogenesis, acts upstream of wash to regulate the d [...] | 0.694 |
Cdc42 | RhoGAP68F | FBpp0301153 | FBpp0306217 | Cdc42 (Cdc42) encodes a GTPase signaling protein that acts as a molecular switch and functions as key regulator of the actin cytoskeleton. It plays a central role in diverse biological processes including actin cytoskeleton organization, mophogenesis, hemocyte migration, cell polarity, and wound repair. | Rho GTPase activating protein at 68F (RhoGAP68F) encodes a GTPase activating protein acting upon small Rho-family GTPases involved in epithelial morphogenesis. It localizes to Rab4 recycling endosomes, forms a complex with the product of Rab4 and modulates the transport of Rab4 recycling endosomes back to the cell surface. | 0.715 |
Cdc42 | RhoGAP71E | FBpp0301153 | FBpp0288504 | Cdc42 (Cdc42) encodes a GTPase signaling protein that acts as a molecular switch and functions as key regulator of the actin cytoskeleton. It plays a central role in diverse biological processes including actin cytoskeleton organization, mophogenesis, hemocyte migration, cell polarity, and wound repair. | Rho GTPase activating protein at 71E (RhoGAP71E) encodes a Rho GTPase activating protein that is involved in the regulation of actin dynamics during epithelial morphogenesis. | 0.583 |
Cdc42 | RhoL | FBpp0301153 | FBpp0293883 | Cdc42 (Cdc42) encodes a GTPase signaling protein that acts as a molecular switch and functions as key regulator of the actin cytoskeleton. It plays a central role in diverse biological processes including actin cytoskeleton organization, mophogenesis, hemocyte migration, cell polarity, and wound repair. | Ras-like GTP-binding protein RhoL; Essential for the maturation of hemocytes. | 0.718 |
GEFmeso | CG6424 | FBpp0289650 | FBpp0086046 | Guanine nucleotide exchange factor in mesoderm (GEFmeso) encodes a protein that regulates the products of Rala and Cdc42. It is involved in leg morphogenesis and wing vein specification. | Uncharacterized protein, isoform A. | 0.495 |
GEFmeso | Cdc42 | FBpp0289650 | FBpp0301153 | Guanine nucleotide exchange factor in mesoderm (GEFmeso) encodes a protein that regulates the products of Rala and Cdc42. It is involved in leg morphogenesis and wing vein specification. | Cdc42 (Cdc42) encodes a GTPase signaling protein that acts as a molecular switch and functions as key regulator of the actin cytoskeleton. It plays a central role in diverse biological processes including actin cytoskeleton organization, mophogenesis, hemocyte migration, cell polarity, and wound repair. | 0.776 |
GEFmeso | Rac1 | FBpp0289650 | FBpp0304252 | Guanine nucleotide exchange factor in mesoderm (GEFmeso) encodes a protein that regulates the products of Rala and Cdc42. It is involved in leg morphogenesis and wing vein specification. | Ras-related protein Rac1; During various developmental processes, regulates changes in cell morphology in response to extracellular signals. During oogenesis, mediates signaling from the tyrosine kinase (RTK) chemoattractant receptors (Egfr and Pvr) to the guidance pathway that control the directional persistent collective migration of the border cell (BC) cluster through the nurse cells to the oocyte. Once activating by Pvr and Egfr, promotes the formation of forward-directed actin protrusions which stabilize the DE- cadherin (shg)-mediated adhesions. In turn, DE-mediated adhesion bet [...] | 0.745 |
GEFmeso | Rho1 | FBpp0289650 | FBpp0086354 | Guanine nucleotide exchange factor in mesoderm (GEFmeso) encodes a protein that regulates the products of Rala and Cdc42. It is involved in leg morphogenesis and wing vein specification. | Ras-like GTP-binding protein Rho1; Has a role in regulating actin cytoskeletal organization: required during early development for proper execution of morphogenetic movements of individual cells and groups of cells important for the formation of the embryonic body plan. Plays a role in regulating dorsal closure during embryogenesis. During axis elongation, required for Rho-kinase Rok planar polarity and adherens junction localization as well as for generating a planar polarized distribution of the actin-binding protein Shrm. During embryogenesis, acts upstream of wash to regulate the d [...] | 0.538 |
GEFmeso | RhoGAP68F | FBpp0289650 | FBpp0306217 | Guanine nucleotide exchange factor in mesoderm (GEFmeso) encodes a protein that regulates the products of Rala and Cdc42. It is involved in leg morphogenesis and wing vein specification. | Rho GTPase activating protein at 68F (RhoGAP68F) encodes a GTPase activating protein acting upon small Rho-family GTPases involved in epithelial morphogenesis. It localizes to Rab4 recycling endosomes, forms a complex with the product of Rab4 and modulates the transport of Rab4 recycling endosomes back to the cell surface. | 0.718 |