STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Est-PEsterase P; Carboxylic ester hydrolase activity; Belongs to the type-B carboxylesterase/lipase family. (544 aa)    
Predicted Functional Partners:
Nlg4
Neuroligin 4 (Nlg4) encodes a synaptic adhesion molecule involved in synapse formation and synaptic transmission.
  
  
 
0.920
Est-6
Esterase-6; Transferred from the ejaculatory bulbs of males to the female genitals upon copulation, plays an important role in the reproductive biology.
  
 
0.904
betaGlu
Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.
    
 0.902
CG15117
Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.
    
 0.902
CG8349
CMP/dCMP-type deaminase domain-containing protein; Cytidine deaminase activity; zinc ion binding. It is involved in the biological process described with: cytidine deamination.
     
  0.900
CG8360
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
     
  0.900
CG8353
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
     
  0.900
Ugt301D1
UDP-glucuronosyltransferase; Transferase activity, transferring hexosyl groups; UDP-glycosyltransferase activity; Belongs to the UDP-glycosyltransferase family.
   
 
  0.653
Ugt49B1
UDP-glucuronosyltransferase; Transferase activity, transferring hexosyl groups; UDP-glycosyltransferase activity. It is involved in the biological process described with: UDP-glucose metabolic process; Belongs to the UDP-glycosyltransferase family.
     
  0.650
Ugt37B1
UDP-glycosyltransferase family 37 member B1; Transferase activity, transferring hexosyl groups; UDP-glycosyltransferase activity. It is involved in the biological process described with: UDP-glucose metabolic process.
     
  0.650
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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