Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CRMP | PlexA | FBpp0112945 | FBpp0088287 | Collapsin Response Mediator Protein (CRMP) encodes a protein that contributes to pyrimidine catabolism, beta-alanine biosynthesis, neurogenesis and behavior. | Plexin A (PlexA) encodes a transmembrane receptor for Semaphorin ligands encoded by Sema1a and Sema1b. The intracellular region of this receptor has GTPase activating protein (GAP) activity on Ras/Rap small GTPases. The signaling by the product of PlexA alters actin, microtubules and cell adhesion in developmental processes such as axon guidance. | 0.770 |
| CRMP | PlexB | FBpp0112945 | FBpp0300616 | Collapsin Response Mediator Protein (CRMP) encodes a protein that contributes to pyrimidine catabolism, beta-alanine biosynthesis, neurogenesis and behavior. | Plexin-B; Involved in peripheral and central nervous system axon guidance. Acts as a receptor for Sema-2a and seems to transduce signal by suppressing Rac activity and enhancing Rho activity. Belongs to the plexin family. | 0.679 |
| CRMP | Sema5c | FBpp0112945 | FBpp0075784 | Collapsin Response Mediator Protein (CRMP) encodes a protein that contributes to pyrimidine catabolism, beta-alanine biosynthesis, neurogenesis and behavior. | Semaphorin 5c (Sema5c) encodes a member of the Semaphorins family, which are membrane and secreted short-range signaling proteins. The product of Sema5c is involved in olfactory behavior. | 0.704 |
| Eph | Ephrin | FBpp0088153 | FBpp0088146 | Eph receptor tyrosine kinase (Eph) encodes an axon guidance molecule involved in the development of the nervous system. It also contributes to shaping the antero-posterior compartment boundary of the wing disc. | Ephrin, isoform A; Ephrin (Ephrin) encodes the ligand of the product of Eph. It is involved in nervous system development; Belongs to the ephrin family. | 0.999 |
| Eph | PlexA | FBpp0088153 | FBpp0088287 | Eph receptor tyrosine kinase (Eph) encodes an axon guidance molecule involved in the development of the nervous system. It also contributes to shaping the antero-posterior compartment boundary of the wing disc. | Plexin A (PlexA) encodes a transmembrane receptor for Semaphorin ligands encoded by Sema1a and Sema1b. The intracellular region of this receptor has GTPase activating protein (GAP) activity on Ras/Rap small GTPases. The signaling by the product of PlexA alters actin, microtubules and cell adhesion in developmental processes such as axon guidance. | 0.726 |
| Eph | PlexB | FBpp0088153 | FBpp0300616 | Eph receptor tyrosine kinase (Eph) encodes an axon guidance molecule involved in the development of the nervous system. It also contributes to shaping the antero-posterior compartment boundary of the wing disc. | Plexin-B; Involved in peripheral and central nervous system axon guidance. Acts as a receptor for Sema-2a and seems to transduce signal by suppressing Rac activity and enhancing Rho activity. Belongs to the plexin family. | 0.704 |
| Eph | Sema5c | FBpp0088153 | FBpp0075784 | Eph receptor tyrosine kinase (Eph) encodes an axon guidance molecule involved in the development of the nervous system. It also contributes to shaping the antero-posterior compartment boundary of the wing disc. | Semaphorin 5c (Sema5c) encodes a member of the Semaphorins family, which are membrane and secreted short-range signaling proteins. The product of Sema5c is involved in olfactory behavior. | 0.688 |
| Eph | robo1 | FBpp0088153 | FBpp0309765 | Eph receptor tyrosine kinase (Eph) encodes an axon guidance molecule involved in the development of the nervous system. It also contributes to shaping the antero-posterior compartment boundary of the wing disc. | Roundabout 1 (robo1) encodes a member of the Robo receptor family that uses the secreted glycoprotein encoded by sli as ligand and the products of Sdc and Dscam1 as co-receptors. It contributes to axon guidance and dendrite morphogenesis as well as regulating trachea and heart tube development. | 0.927 |
| Eph | robo2 | FBpp0088153 | FBpp0303020 | Eph receptor tyrosine kinase (Eph) encodes an axon guidance molecule involved in the development of the nervous system. It also contributes to shaping the antero-posterior compartment boundary of the wing disc. | Roundabout 2 (robo2) encodes a member of the Robo receptor family that responds to the ligand encoded by sli as a repulsive cue in axons, dendrites, muscles, trachea and heart development. It can also inhibit robo1 signaling, likely explaining why the product of robo2 can appear to be an attractive receptor in certain contexts. | 0.909 |
| Eph | robo3 | FBpp0088153 | FBpp0307368 | Eph receptor tyrosine kinase (Eph) encodes an axon guidance molecule involved in the development of the nervous system. It also contributes to shaping the antero-posterior compartment boundary of the wing disc. | Roundabout 3, isoform A. | 0.909 |
| Eph | sli | FBpp0088153 | FBpp0303578 | Eph receptor tyrosine kinase (Eph) encodes an axon guidance molecule involved in the development of the nervous system. It also contributes to shaping the antero-posterior compartment boundary of the wing disc. | Slit (sli) encodes a secreted glycoprotein that acts as a ligand for the Robo receptor family and co-receptors, including the products of Sdc and Dscam1. The product of sli functions as second messenger (via Abl) and receptor dependent, providing repellent (neural growth cone), attractive (trachea), and polarising (cardioblasts) cues for differentiating cells. | 0.646 |
| Eph | tsr | FBpp0088153 | FBpp0072097 | Eph receptor tyrosine kinase (Eph) encodes an axon guidance molecule involved in the development of the nervous system. It also contributes to shaping the antero-posterior compartment boundary of the wing disc. | Cofilin/actin-depolymerizing factor homolog; Exhibits F-actin depolymerizing activity and regulates actin cytoskeleton dynamics. Required for cytokinesis in both mitotic and meiotic cells and for aster migration and separation. Promotes cell motility during ovary development and oogenesis. During larval development, required for the cell rearrangement needed for formation of terminal filaments which are stacks of somatic cells that are important for the initiation of ovarioles. Also required for border cell migration during oogenesis. During border cell migration, required for actin tu [...] | 0.446 |
| Ephrin | Eph | FBpp0088146 | FBpp0088153 | Ephrin, isoform A; Ephrin (Ephrin) encodes the ligand of the product of Eph. It is involved in nervous system development; Belongs to the ephrin family. | Eph receptor tyrosine kinase (Eph) encodes an axon guidance molecule involved in the development of the nervous system. It also contributes to shaping the antero-posterior compartment boundary of the wing disc. | 0.999 |
| Ephrin | PlexA | FBpp0088146 | FBpp0088287 | Ephrin, isoform A; Ephrin (Ephrin) encodes the ligand of the product of Eph. It is involved in nervous system development; Belongs to the ephrin family. | Plexin A (PlexA) encodes a transmembrane receptor for Semaphorin ligands encoded by Sema1a and Sema1b. The intracellular region of this receptor has GTPase activating protein (GAP) activity on Ras/Rap small GTPases. The signaling by the product of PlexA alters actin, microtubules and cell adhesion in developmental processes such as axon guidance. | 0.876 |
| Ephrin | PlexB | FBpp0088146 | FBpp0300616 | Ephrin, isoform A; Ephrin (Ephrin) encodes the ligand of the product of Eph. It is involved in nervous system development; Belongs to the ephrin family. | Plexin-B; Involved in peripheral and central nervous system axon guidance. Acts as a receptor for Sema-2a and seems to transduce signal by suppressing Rac activity and enhancing Rho activity. Belongs to the plexin family. | 0.544 |
| Ephrin | Sema5c | FBpp0088146 | FBpp0075784 | Ephrin, isoform A; Ephrin (Ephrin) encodes the ligand of the product of Eph. It is involved in nervous system development; Belongs to the ephrin family. | Semaphorin 5c (Sema5c) encodes a member of the Semaphorins family, which are membrane and secreted short-range signaling proteins. The product of Sema5c is involved in olfactory behavior. | 0.696 |
| Ephrin | robo1 | FBpp0088146 | FBpp0309765 | Ephrin, isoform A; Ephrin (Ephrin) encodes the ligand of the product of Eph. It is involved in nervous system development; Belongs to the ephrin family. | Roundabout 1 (robo1) encodes a member of the Robo receptor family that uses the secreted glycoprotein encoded by sli as ligand and the products of Sdc and Dscam1 as co-receptors. It contributes to axon guidance and dendrite morphogenesis as well as regulating trachea and heart tube development. | 0.883 |
| Ephrin | robo2 | FBpp0088146 | FBpp0303020 | Ephrin, isoform A; Ephrin (Ephrin) encodes the ligand of the product of Eph. It is involved in nervous system development; Belongs to the ephrin family. | Roundabout 2 (robo2) encodes a member of the Robo receptor family that responds to the ligand encoded by sli as a repulsive cue in axons, dendrites, muscles, trachea and heart development. It can also inhibit robo1 signaling, likely explaining why the product of robo2 can appear to be an attractive receptor in certain contexts. | 0.818 |
| Ephrin | robo3 | FBpp0088146 | FBpp0307368 | Ephrin, isoform A; Ephrin (Ephrin) encodes the ligand of the product of Eph. It is involved in nervous system development; Belongs to the ephrin family. | Roundabout 3, isoform A. | 0.813 |
| Ephrin | sli | FBpp0088146 | FBpp0303578 | Ephrin, isoform A; Ephrin (Ephrin) encodes the ligand of the product of Eph. It is involved in nervous system development; Belongs to the ephrin family. | Slit (sli) encodes a secreted glycoprotein that acts as a ligand for the Robo receptor family and co-receptors, including the products of Sdc and Dscam1. The product of sli functions as second messenger (via Abl) and receptor dependent, providing repellent (neural growth cone), attractive (trachea), and polarising (cardioblasts) cues for differentiating cells. | 0.560 |
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