| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CG43896 | prc | FBpp0311737 | FBpp0075796 | Uncharacterized protein, isoform C; Chitin binding. It is involved in the biological process described with: chitin metabolic process. | Pericardin (prc) encodes a type IV collagen-like extracellular matrix protein involved in heart development. | 0.562 |
| Col4a1 | LanA | FBpp0078641 | FBpp0076722 | Collagen alpha-1(IV) chain; Collagen type IV alpha 1 (Col4a1) encodes a subunit of Collagen IV and a major component of basement membranes. It is required for muscle and epithelium integrity. | Laminin subunit alpha; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Activates presynaptic signaling involving integrin alpha-PS3/beta-nu and Fak to suppress neuromuscular junction (NMJ) growth during larval development and during low crawling activity, but not during higher-crawling conditions. Mediates, together with integrin alpha-PS3/beta-nu, glutamate receptor-modulated NMJ growth. | 0.833 |
| Col4a1 | LanB1 | FBpp0078641 | FBpp0079113 | Collagen alpha-1(IV) chain; Collagen type IV alpha 1 (Col4a1) encodes a subunit of Collagen IV and a major component of basement membranes. It is required for muscle and epithelium integrity. | LanB1 (LanB1) encodes a subunit of laminin, a heterotrimeric protein found in the extracellular matrix (ECM) and a major component of the basal lamina. Laminins interact with a variety of cell surface molecules such as integrin receptors and other secreted ECM components. It contributes to ECM organization, tissue adhesion, cell motility and developmental patterning. | 0.873 |
| Col4a1 | LanB2 | FBpp0078641 | FBpp0311281 | Collagen alpha-1(IV) chain; Collagen type IV alpha 1 (Col4a1) encodes a subunit of Collagen IV and a major component of basement membranes. It is required for muscle and epithelium integrity. | Laminin B2 (LanB2) encodes a subunit of laminin, a heterotrimeric protein found in the extracellular matrix (ECM) and a major component of the basal lamina. Laminins interact with a variety of cell surface molecules such as integrin receptors and other secreted ECM components. It contributes to ECM organization, tissue adhesion, cell motility and developmental patterning. | 0.885 |
| Col4a1 | loh | FBpp0078641 | FBpp0079619 | Collagen alpha-1(IV) chain; Collagen type IV alpha 1 (Col4a1) encodes a subunit of Collagen IV and a major component of basement membranes. It is required for muscle and epithelium integrity. | Lonely heart (loh) encodes a protein involved in larval heart development and regulation of the extracellular matrix assembly. | 0.469 |
| Col4a1 | prc | FBpp0078641 | FBpp0075796 | Collagen alpha-1(IV) chain; Collagen type IV alpha 1 (Col4a1) encodes a subunit of Collagen IV and a major component of basement membranes. It is required for muscle and epithelium integrity. | Pericardin (prc) encodes a type IV collagen-like extracellular matrix protein involved in heart development. | 0.941 |
| Col4a1 | vkg | FBpp0078641 | FBpp0305721 | Collagen alpha-1(IV) chain; Collagen type IV alpha 1 (Col4a1) encodes a subunit of Collagen IV and a major component of basement membranes. It is required for muscle and epithelium integrity. | Viking, isoform A; Viking (vkg) encodes a subunit of Collagen IV and a major component of basement membranes. It is secreted by haemocytes and fat body cells and is required for the normal morphogenesis of many tissues. It also contributes to TGF-beta signalling in the early embryo and the developing Malpighian tubules. | 0.999 |
| Hand | Mef2 | FBpp0079662 | FBpp0303551 | FI14601p; Hand (Hand) encodes a transcription factor that contributes to cardiogenesis, hemopoiesis, and muscle function. | Myocyte-specific enhancer factor 2; Transcription factor that could be a key player in early mesoderm differentiation and may be required for subsequent cell fate specifications within the somatic and visceral/heart mesodermal layers. Essential for myoblast fusion and consequently muscle formation in adults. During embryonic and pupal development, binds to the enhancer of the myoblast fusion gene sing and activates its transcription. Belongs to the MEF2 family. | 0.593 |
| Hand | loh | FBpp0079662 | FBpp0079619 | FI14601p; Hand (Hand) encodes a transcription factor that contributes to cardiogenesis, hemopoiesis, and muscle function. | Lonely heart (loh) encodes a protein involved in larval heart development and regulation of the extracellular matrix assembly. | 0.450 |
| Hand | prc | FBpp0079662 | FBpp0075796 | FI14601p; Hand (Hand) encodes a transcription factor that contributes to cardiogenesis, hemopoiesis, and muscle function. | Pericardin (prc) encodes a type IV collagen-like extracellular matrix protein involved in heart development. | 0.609 |
| Hand | tin | FBpp0079662 | FBpp0083485 | FI14601p; Hand (Hand) encodes a transcription factor that contributes to cardiogenesis, hemopoiesis, and muscle function. | Muscle-specific homeobox protein tinman; Required for the development of heart and visceral muscle; for the formation of somatic muscles. Has a crucial function in the early mesodermal subdivisions. | 0.888 |
| LanA | Col4a1 | FBpp0076722 | FBpp0078641 | Laminin subunit alpha; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Activates presynaptic signaling involving integrin alpha-PS3/beta-nu and Fak to suppress neuromuscular junction (NMJ) growth during larval development and during low crawling activity, but not during higher-crawling conditions. Mediates, together with integrin alpha-PS3/beta-nu, glutamate receptor-modulated NMJ growth. | Collagen alpha-1(IV) chain; Collagen type IV alpha 1 (Col4a1) encodes a subunit of Collagen IV and a major component of basement membranes. It is required for muscle and epithelium integrity. | 0.833 |
| LanA | LanB1 | FBpp0076722 | FBpp0079113 | Laminin subunit alpha; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Activates presynaptic signaling involving integrin alpha-PS3/beta-nu and Fak to suppress neuromuscular junction (NMJ) growth during larval development and during low crawling activity, but not during higher-crawling conditions. Mediates, together with integrin alpha-PS3/beta-nu, glutamate receptor-modulated NMJ growth. | LanB1 (LanB1) encodes a subunit of laminin, a heterotrimeric protein found in the extracellular matrix (ECM) and a major component of the basal lamina. Laminins interact with a variety of cell surface molecules such as integrin receptors and other secreted ECM components. It contributes to ECM organization, tissue adhesion, cell motility and developmental patterning. | 0.976 |
| LanA | LanB2 | FBpp0076722 | FBpp0311281 | Laminin subunit alpha; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Activates presynaptic signaling involving integrin alpha-PS3/beta-nu and Fak to suppress neuromuscular junction (NMJ) growth during larval development and during low crawling activity, but not during higher-crawling conditions. Mediates, together with integrin alpha-PS3/beta-nu, glutamate receptor-modulated NMJ growth. | Laminin B2 (LanB2) encodes a subunit of laminin, a heterotrimeric protein found in the extracellular matrix (ECM) and a major component of the basal lamina. Laminins interact with a variety of cell surface molecules such as integrin receptors and other secreted ECM components. It contributes to ECM organization, tissue adhesion, cell motility and developmental patterning. | 0.993 |
| LanA | prc | FBpp0076722 | FBpp0075796 | Laminin subunit alpha; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Activates presynaptic signaling involving integrin alpha-PS3/beta-nu and Fak to suppress neuromuscular junction (NMJ) growth during larval development and during low crawling activity, but not during higher-crawling conditions. Mediates, together with integrin alpha-PS3/beta-nu, glutamate receptor-modulated NMJ growth. | Pericardin (prc) encodes a type IV collagen-like extracellular matrix protein involved in heart development. | 0.770 |
| LanA | vkg | FBpp0076722 | FBpp0305721 | Laminin subunit alpha; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Activates presynaptic signaling involving integrin alpha-PS3/beta-nu and Fak to suppress neuromuscular junction (NMJ) growth during larval development and during low crawling activity, but not during higher-crawling conditions. Mediates, together with integrin alpha-PS3/beta-nu, glutamate receptor-modulated NMJ growth. | Viking, isoform A; Viking (vkg) encodes a subunit of Collagen IV and a major component of basement membranes. It is secreted by haemocytes and fat body cells and is required for the normal morphogenesis of many tissues. It also contributes to TGF-beta signalling in the early embryo and the developing Malpighian tubules. | 0.944 |
| LanB1 | Col4a1 | FBpp0079113 | FBpp0078641 | LanB1 (LanB1) encodes a subunit of laminin, a heterotrimeric protein found in the extracellular matrix (ECM) and a major component of the basal lamina. Laminins interact with a variety of cell surface molecules such as integrin receptors and other secreted ECM components. It contributes to ECM organization, tissue adhesion, cell motility and developmental patterning. | Collagen alpha-1(IV) chain; Collagen type IV alpha 1 (Col4a1) encodes a subunit of Collagen IV and a major component of basement membranes. It is required for muscle and epithelium integrity. | 0.873 |
| LanB1 | LanA | FBpp0079113 | FBpp0076722 | LanB1 (LanB1) encodes a subunit of laminin, a heterotrimeric protein found in the extracellular matrix (ECM) and a major component of the basal lamina. Laminins interact with a variety of cell surface molecules such as integrin receptors and other secreted ECM components. It contributes to ECM organization, tissue adhesion, cell motility and developmental patterning. | Laminin subunit alpha; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Activates presynaptic signaling involving integrin alpha-PS3/beta-nu and Fak to suppress neuromuscular junction (NMJ) growth during larval development and during low crawling activity, but not during higher-crawling conditions. Mediates, together with integrin alpha-PS3/beta-nu, glutamate receptor-modulated NMJ growth. | 0.976 |
| LanB1 | LanB2 | FBpp0079113 | FBpp0311281 | LanB1 (LanB1) encodes a subunit of laminin, a heterotrimeric protein found in the extracellular matrix (ECM) and a major component of the basal lamina. Laminins interact with a variety of cell surface molecules such as integrin receptors and other secreted ECM components. It contributes to ECM organization, tissue adhesion, cell motility and developmental patterning. | Laminin B2 (LanB2) encodes a subunit of laminin, a heterotrimeric protein found in the extracellular matrix (ECM) and a major component of the basal lamina. Laminins interact with a variety of cell surface molecules such as integrin receptors and other secreted ECM components. It contributes to ECM organization, tissue adhesion, cell motility and developmental patterning. | 0.996 |
| LanB1 | loh | FBpp0079113 | FBpp0079619 | LanB1 (LanB1) encodes a subunit of laminin, a heterotrimeric protein found in the extracellular matrix (ECM) and a major component of the basal lamina. Laminins interact with a variety of cell surface molecules such as integrin receptors and other secreted ECM components. It contributes to ECM organization, tissue adhesion, cell motility and developmental patterning. | Lonely heart (loh) encodes a protein involved in larval heart development and regulation of the extracellular matrix assembly. | 0.429 |
STRING v12.5 is now available!
