CG8009 protein (fruit fly) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Drosophila melanogaster

NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CG41106	CG8009	FBpp0110553	FBpp0075984	MIP26267p; It is involved in the biological process described with: positive regulation of protein dephosphorylation.	Nuclear envelope phosphatase-regulatory subunit 1 homolog; May form with the serine/threonine protein phosphatase l(1)G0269 an active complex dephosphorylating and activating lipin-like phosphatases. Lipins are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels (By similarity).	0.918
CG41106	Dd	FBpp0110553	FBpp0076921	MIP26267p; It is involved in the biological process described with: positive regulation of protein dephosphorylation.	CTD nuclear envelope phosphatase 1 homolog; Serine/threonine protein phosphatase that may dephosphorylate and activate lipin-like phosphatases. Lipins are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol (By similarity). Belongs to t [...]	0.993
CG41106	Dgk	FBpp0110553	FBpp0300813	MIP26267p; It is involved in the biological process described with: positive regulation of protein dephosphorylation.	Diacylglycerol kinase 1; Upon cell stimulation converts the second messenger diacylglycerol into phosphatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity (By similarity). May have a role in the development of the embryonic nervous system and the function of the adult nervous system and muscle; regulating signal transduction in neurons.	0.602
CG41106	TORIP	FBpp0110553	FBpp0306010	MIP26267p; It is involved in the biological process described with: positive regulation of protein dephosphorylation.	Torsin interacting protein, isoform A.	0.655
CG8009	CG41106	FBpp0075984	FBpp0110553	Nuclear envelope phosphatase-regulatory subunit 1 homolog; May form with the serine/threonine protein phosphatase l(1)G0269 an active complex dephosphorylating and activating lipin-like phosphatases. Lipins are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels (By similarity).	MIP26267p; It is involved in the biological process described with: positive regulation of protein dephosphorylation.	0.918
CG8009	Dd	FBpp0075984	FBpp0076921	Nuclear envelope phosphatase-regulatory subunit 1 homolog; May form with the serine/threonine protein phosphatase l(1)G0269 an active complex dephosphorylating and activating lipin-like phosphatases. Lipins are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels (By similarity).	CTD nuclear envelope phosphatase 1 homolog; Serine/threonine protein phosphatase that may dephosphorylate and activate lipin-like phosphatases. Lipins are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol (By similarity). Belongs to t [...]	0.976
CG8009	Dgk	FBpp0075984	FBpp0300813	Nuclear envelope phosphatase-regulatory subunit 1 homolog; May form with the serine/threonine protein phosphatase l(1)G0269 an active complex dephosphorylating and activating lipin-like phosphatases. Lipins are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels (By similarity).	Diacylglycerol kinase 1; Upon cell stimulation converts the second messenger diacylglycerol into phosphatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity (By similarity). May have a role in the development of the embryonic nervous system and the function of the adult nervous system and muscle; regulating signal transduction in neurons.	0.539
CG8009	Lpin	FBpp0075984	FBpp0292618	Nuclear envelope phosphatase-regulatory subunit 1 homolog; May form with the serine/threonine protein phosphatase l(1)G0269 an active complex dephosphorylating and activating lipin-like phosphatases. Lipins are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels (By similarity).	Lipin, isoform A; Lipin (Lpin) encodes a protein that plays a central role in fat body function and energy metabolism. It works as a phosphatidate phosphatase required for normal insulin pathway signaling.	0.874
CG8009	TORIP	FBpp0075984	FBpp0306010	Nuclear envelope phosphatase-regulatory subunit 1 homolog; May form with the serine/threonine protein phosphatase l(1)G0269 an active complex dephosphorylating and activating lipin-like phosphatases. Lipins are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels (By similarity).	Torsin interacting protein, isoform A.	0.668
CG8009	Torsin	FBpp0075984	FBpp0311758	Nuclear envelope phosphatase-regulatory subunit 1 homolog; May form with the serine/threonine protein phosphatase l(1)G0269 an active complex dephosphorylating and activating lipin-like phosphatases. Lipins are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels (By similarity).	Torsin-like protein; Torsin (Torsin) encodes an AAA-ATPase that is implicated in the export of large ribonuclear protein particles through the nuclear membrane. It regulates dopamine levels; Belongs to the ClpA/ClpB family. Torsin subfamily.	0.667
Dd	CG41106	FBpp0076921	FBpp0110553	CTD nuclear envelope phosphatase 1 homolog; Serine/threonine protein phosphatase that may dephosphorylate and activate lipin-like phosphatases. Lipins are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol (By similarity). Belongs to t [...]	MIP26267p; It is involved in the biological process described with: positive regulation of protein dephosphorylation.	0.993
Dd	CG8009	FBpp0076921	FBpp0075984	CTD nuclear envelope phosphatase 1 homolog; Serine/threonine protein phosphatase that may dephosphorylate and activate lipin-like phosphatases. Lipins are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol (By similarity). Belongs to t [...]	Nuclear envelope phosphatase-regulatory subunit 1 homolog; May form with the serine/threonine protein phosphatase l(1)G0269 an active complex dephosphorylating and activating lipin-like phosphatases. Lipins are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels (By similarity).	0.976
Dd	Dgk	FBpp0076921	FBpp0300813	CTD nuclear envelope phosphatase 1 homolog; Serine/threonine protein phosphatase that may dephosphorylate and activate lipin-like phosphatases. Lipins are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol (By similarity). Belongs to t [...]	Diacylglycerol kinase 1; Upon cell stimulation converts the second messenger diacylglycerol into phosphatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity (By similarity). May have a role in the development of the embryonic nervous system and the function of the adult nervous system and muscle; regulating signal transduction in neurons.	0.473
Dd	Lpin	FBpp0076921	FBpp0292618	CTD nuclear envelope phosphatase 1 homolog; Serine/threonine protein phosphatase that may dephosphorylate and activate lipin-like phosphatases. Lipins are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol (By similarity). Belongs to t [...]	Lipin, isoform A; Lipin (Lpin) encodes a protein that plays a central role in fat body function and energy metabolism. It works as a phosphatidate phosphatase required for normal insulin pathway signaling.	0.974
Dd	TORIP	FBpp0076921	FBpp0306010	CTD nuclear envelope phosphatase 1 homolog; Serine/threonine protein phosphatase that may dephosphorylate and activate lipin-like phosphatases. Lipins are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol (By similarity). Belongs to t [...]	Torsin interacting protein, isoform A.	0.604
Dgk	CG41106	FBpp0300813	FBpp0110553	Diacylglycerol kinase 1; Upon cell stimulation converts the second messenger diacylglycerol into phosphatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity (By similarity). May have a role in the development of the embryonic nervous system and the function of the adult nervous system and muscle; regulating signal transduction in neurons.	MIP26267p; It is involved in the biological process described with: positive regulation of protein dephosphorylation.	0.602
Dgk	CG8009	FBpp0300813	FBpp0075984	Diacylglycerol kinase 1; Upon cell stimulation converts the second messenger diacylglycerol into phosphatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity (By similarity). May have a role in the development of the embryonic nervous system and the function of the adult nervous system and muscle; regulating signal transduction in neurons.	Nuclear envelope phosphatase-regulatory subunit 1 homolog; May form with the serine/threonine protein phosphatase l(1)G0269 an active complex dephosphorylating and activating lipin-like phosphatases. Lipins are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels (By similarity).	0.539
Dgk	Dd	FBpp0300813	FBpp0076921	Diacylglycerol kinase 1; Upon cell stimulation converts the second messenger diacylglycerol into phosphatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity (By similarity). May have a role in the development of the embryonic nervous system and the function of the adult nervous system and muscle; regulating signal transduction in neurons.	CTD nuclear envelope phosphatase 1 homolog; Serine/threonine protein phosphatase that may dephosphorylate and activate lipin-like phosphatases. Lipins are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol (By similarity). Belongs to t [...]	0.473
Dgk	Lpin	FBpp0300813	FBpp0292618	Diacylglycerol kinase 1; Upon cell stimulation converts the second messenger diacylglycerol into phosphatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity (By similarity). May have a role in the development of the embryonic nervous system and the function of the adult nervous system and muscle; regulating signal transduction in neurons.	Lipin, isoform A; Lipin (Lpin) encodes a protein that plays a central role in fat body function and energy metabolism. It works as a phosphatidate phosphatase required for normal insulin pathway signaling.	0.541
Dgk	TORIP	FBpp0300813	FBpp0306010	Diacylglycerol kinase 1; Upon cell stimulation converts the second messenger diacylglycerol into phosphatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity (By similarity). May have a role in the development of the embryonic nervous system and the function of the adult nervous system and muscle; regulating signal transduction in neurons.	Torsin interacting protein, isoform A.	0.472