STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG32066GH09096p. (324 aa)    
Predicted Functional Partners:
Ddx1
ATP-dependent RNA helicase Ddx1; Dead-box-1 (Ddx1) encodes a member of the DEAD box family of RNA helicases that bind and unwind double-stranded RNA. Ddx1 product depletion is associated with small size and aberrant gametogenesis, possibly through alternative splicing of Sirup RNA transcript.
      
 0.812
CG4393
IP14385p.
    
   0.664
CG33111
FI03658p.
      
 0.653
ras
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
      
 0.607
CG33172
MIP10235p; RNA binding. It is involved in the biological process described with: negative regulation of cell population proliferation.
   
  
 0.604
CG7156
LD24550p; Protein serine/threonine kinase activity; phosphatidylinositol binding; ATP binding. It is involved in the biological process described with: protein phosphorylation.
      
 0.597
Tasp1
Taspase 1 (Tasp1) encodes a threonine-type endopeptidase involved in spermatogenesis and the defense response to Gram-negative bacteria.
      
 0.576
CG3704
GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.
      
 0.545
dsx-c73A
Doublesex cognate 73A (dsx-c73A) encodes a secreted cuticle protein present in the epidermis, salivary duct and trachea. The epidermal expression is under the control of the product of ovo.
      
 0.520
Asap
ArfGAP with SH3 domain, ANK repeat and PH domain-containing protein; Probable GTPase-activating protein (GAP) for Arf family proteins (Probable). Involved in Golgi apparatus organization by targeting Arf1 to the Golgi, which may be important for membrane trafficking during epithelial morphogenesis. Regulates the positioning of interommatidial precursor cells during compound eye morphogenesis together with Arf6 and Cindr. Required for cleavage furrow ingression in early embryonic cells.
      
 0.517
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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