STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CalpBCalpain-B catalytic subunit 1; Calcium-regulated non-lysosomal thiol-protease. (925 aa)    
Predicted Functional Partners:
CG8311
Uncharacterized protein; Dolichol kinase activity. It is involved in the biological process described with: dolichyl monophosphate biosynthetic process.
   
 
 0.665
UK114
RutC family protein UK114; Molecular chaperone. Seems to fulfill an ATP-independent, HSP70-like function in protein folding. May protect essential factors of cell proliferation during heat shock. No role in calpain activation.
      
 0.665
CG14492
Uncharacterized protein.
      
 0.662
CG30466
Uncharacterized protein, isoform B; It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process.
      
 0.662
CG5639
Uncharacterized protein; Serine-type endopeptidase inhibitor activity.
    
 
 0.657
mys
Integrin beta-PS; Integrin alpha-PS1/beta-PS is a receptor for laminin. Integrin alpha-PS2/beta-PS is a receptor for Tig, wb and Ten-m. Contributes to endodermal integrity and adhesion between the midgut epithelium and the surrounding visceral muscle. Essential for migration of the primordial midgut cells and for maintaining, but not establishing, cell polarity in the midgut epithelium. The two beta subunits mediate midgut migration by distinct mechanisms: beta-PS requires rhea/talin and Itgbn does not. Required for rhea/talin correct cellular localization in the midgut. Required for m [...]
   
 
 0.596
CG17765
GH27120p; Calcium ion binding.
   
 
0.587
Alg-2
Apoptosis-linked gene-2; Calcium ion binding. It is involved in the biological process described with: positive regulation of JNK cascade.
   
 
0.587
CG5618
LP10922p; Pyridoxal phosphate binding; glutamate decarboxylase activity. It is involved in the biological process described with: carboxylic acid metabolic process.
   
  
 0.543
SCaMC
Short Calcium-binding Mitochondrial Carrier (SCaMC) encodes a mitochondrial carrier family protein with calcium-binding motifs. SCaMC transcripts are strongly detected in the corpora allata, suggesting its potential role in juvenile hormone biosynthesis.
 
 
 
 0.538
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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