Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CG18178GH03795p; Nucleic acid binding. It is involved in the biological process described with: maturation of 5.8S rRNA; maturation of LSU-rRNA. (374 aa)    
Predicted Functional Partners:
CG1542
Probable rRNA-processing protein EBP2 homolog; Required for the processing of the 27S pre-rRNA. Belongs to the EBP2 family.
   
 0.968
Nlp
Nucleoplasmin-like protein; Binds to core histones and functions in the ATP-facilitated assembly of approximately regularly spaced nucleosomal arrays. May participate in parallel with other histone-binding proteins such as NAP-1; Belongs to the nucleoplasmin family.
   
 
 0.962
Nph
Nucleophosmin, isoform A; Nucleophosmin (Nph) encodes a histone binding protein involved in chromatin remodeling and sperm chromatin decondensation.
   
 
 0.962
ppan
Protein Peter pan; Required for initiation of larval growth and normal mitotic growth but is not absolutely required for general biosynthesis or DNA replication. Required for progression of normal oogenesis and maturation of some imaginal tissues into adult structures.
   
 0.954
CG32409
Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family.
   
 0.953
CG8939
Putative rRNA methyltransferase; Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits.
   
 0.950
CG5033
Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family.
   
 0.946
Ip259
Intronic protein 259, isoform A; It is involved in the biological process described with: maturation of LSU-rRNA; maturation of 5.8S rRNA.
   
  0.929
CG3817
RRP15-like protein; It is involved in the biological process described with: maturation of 5.8S rRNA; maturation of LSU-rRNA; Belongs to the RRP15 family.
   
 0.926
l(2)k09848
Lethal (2) k09848, isoform A; It is involved in the biological process described with: muscle cell cellular homeostasis; ribosomal large subunit biogenesis.
   
 
 0.926
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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