| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AdSL | AdSS | FBpp0082816 | FBpp0083395 | Adenylosuccinate Lyase (AdSL) encodes a protein that might be a lyase involved in purine nucleotide metabolic process based on orthology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Plays a role in the regulation of adult life span. | 0.999 |
| AdSL | Aprt | FBpp0082816 | FBpp0312099 | Adenylosuccinate Lyase (AdSL) encodes a protein that might be a lyase involved in purine nucleotide metabolic process based on orthology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.993 |
| AdSL | CG2246 | FBpp0082816 | FBpp0085035 | Adenylosuccinate Lyase (AdSL) encodes a protein that might be a lyase involved in purine nucleotide metabolic process based on orthology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | GH23275p; Magnesium ion binding; ribose phosphate diphosphokinase activity. It is involved in the biological process described with: nucleotide biosynthetic process; 5-phosphoribose 1-diphosphate biosynthetic process; nucleoside metabolic process; purine nucleotide biosynthetic process. | 0.718 |
| AdSL | Gart | FBpp0082816 | FBpp0308722 | Adenylosuccinate Lyase (AdSL) encodes a protein that might be a lyase involved in purine nucleotide metabolic process based on orthology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Trifunctional purine biosynthetic protein adenosine-3; GART trifunctional enzyme (Gart) encodes a multifunctional enzyme that exhibits phosphoribosylamine-glycine ligase, phosphoribosylformylglycinamidine cyclo-ligase and phosphoribosylglycinamide formyltransferase activities; In the N-terminal section; belongs to the GARS family. In the C-terminal section; belongs to the GART family. | 0.999 |
| AdSL | GluProRS | FBpp0082816 | FBpp0083898 | Adenylosuccinate Lyase (AdSL) encodes a protein that might be a lyase involved in purine nucleotide metabolic process based on orthology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Bifunctional glutamate/proline--tRNA ligase; Catalyzes the attachment of the cognate amino acid to the corresponding tRNA in a two-step reaction: the amino acid is first activated by ATP to form a covalent intermediate with AMP and is then transferred to the acceptor end of the cognate tRNA. In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family. | 0.669 |
| AdSL | LysRS | FBpp0082816 | FBpp0071302 | Adenylosuccinate Lyase (AdSL) encodes a protein that might be a lyase involved in purine nucleotide metabolic process based on orthology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Lysine--tRNA ligase; tRNA binding; ATP binding; lysine-tRNA ligase activity. It is involved in the biological process described with: lysyl-tRNA aminoacylation. | 0.426 |
| AdSL | Prps | FBpp0082816 | FBpp0076145 | Adenylosuccinate Lyase (AdSL) encodes a protein that might be a lyase involved in purine nucleotide metabolic process based on orthology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Uncharacterized protein, isoform B; Magnesium ion binding; ATP binding; ribose phosphate diphosphokinase activity. It is involved in the biological process described with: ribonucleoside monophosphate biosynthetic process; purine nucleotide biosynthetic process; nucleoside metabolic process; nucleotide biosynthetic process; 5-phosphoribose 1-diphosphate biosynthetic process. | 0.827 |
| AdSL | bur | FBpp0082816 | FBpp0310411 | Adenylosuccinate Lyase (AdSL) encodes a protein that might be a lyase involved in purine nucleotide metabolic process based on orthology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Burgundy, isoform B; Burgundy (bur) encodes a GMP synthetase required for axon guidance. It regulates the activity of the ubiquitin protease encoded by Usp7. | 0.905 |
| AdSS | AdSL | FBpp0083395 | FBpp0082816 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Plays a role in the regulation of adult life span. | Adenylosuccinate Lyase (AdSL) encodes a protein that might be a lyase involved in purine nucleotide metabolic process based on orthology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.999 |
| AdSS | Aprt | FBpp0083395 | FBpp0312099 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Plays a role in the regulation of adult life span. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.876 |
| AdSS | CG2246 | FBpp0083395 | FBpp0085035 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Plays a role in the regulation of adult life span. | GH23275p; Magnesium ion binding; ribose phosphate diphosphokinase activity. It is involved in the biological process described with: nucleotide biosynthetic process; 5-phosphoribose 1-diphosphate biosynthetic process; nucleoside metabolic process; purine nucleotide biosynthetic process. | 0.564 |
| AdSS | Gart | FBpp0083395 | FBpp0308722 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Plays a role in the regulation of adult life span. | Trifunctional purine biosynthetic protein adenosine-3; GART trifunctional enzyme (Gart) encodes a multifunctional enzyme that exhibits phosphoribosylamine-glycine ligase, phosphoribosylformylglycinamidine cyclo-ligase and phosphoribosylglycinamide formyltransferase activities; In the N-terminal section; belongs to the GARS family. In the C-terminal section; belongs to the GART family. | 0.999 |
| AdSS | GluProRS | FBpp0083395 | FBpp0083898 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Plays a role in the regulation of adult life span. | Bifunctional glutamate/proline--tRNA ligase; Catalyzes the attachment of the cognate amino acid to the corresponding tRNA in a two-step reaction: the amino acid is first activated by ATP to form a covalent intermediate with AMP and is then transferred to the acceptor end of the cognate tRNA. In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family. | 0.570 |
| AdSS | Prps | FBpp0083395 | FBpp0076145 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Plays a role in the regulation of adult life span. | Uncharacterized protein, isoform B; Magnesium ion binding; ATP binding; ribose phosphate diphosphokinase activity. It is involved in the biological process described with: ribonucleoside monophosphate biosynthetic process; purine nucleotide biosynthetic process; nucleoside metabolic process; nucleotide biosynthetic process; 5-phosphoribose 1-diphosphate biosynthetic process. | 0.836 |
| AdSS | Rpe | FBpp0083395 | FBpp0088028 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Plays a role in the regulation of adult life span. | Metal ion binding; ribulose-phosphate 3-epimerase activity. It is involved in the biological process described with: cellular carbohydrate metabolic process; pentose catabolic process; pentose-phosphate shunt, non-oxidative branch. | 0.702 |
| AdSS | bur | FBpp0083395 | FBpp0310411 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Plays a role in the regulation of adult life span. | Burgundy, isoform B; Burgundy (bur) encodes a GMP synthetase required for axon guidance. It regulates the activity of the ubiquitin protease encoded by Usp7. | 0.876 |
| Aprt | AdSL | FBpp0312099 | FBpp0082816 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Adenylosuccinate Lyase (AdSL) encodes a protein that might be a lyase involved in purine nucleotide metabolic process based on orthology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.993 |
| Aprt | AdSS | FBpp0312099 | FBpp0083395 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Plays a role in the regulation of adult life span. | 0.876 |
| Aprt | CG2246 | FBpp0312099 | FBpp0085035 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GH23275p; Magnesium ion binding; ribose phosphate diphosphokinase activity. It is involved in the biological process described with: nucleotide biosynthetic process; 5-phosphoribose 1-diphosphate biosynthetic process; nucleoside metabolic process; purine nucleotide biosynthetic process. | 0.655 |
| Aprt | Gart | FBpp0312099 | FBpp0308722 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Trifunctional purine biosynthetic protein adenosine-3; GART trifunctional enzyme (Gart) encodes a multifunctional enzyme that exhibits phosphoribosylamine-glycine ligase, phosphoribosylformylglycinamidine cyclo-ligase and phosphoribosylglycinamide formyltransferase activities; In the N-terminal section; belongs to the GARS family. In the C-terminal section; belongs to the GART family. | 0.965 |
STRING v12.5 is now available!
