STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pathProton-coupled amino acid transporter-like protein pathetic; Amino acid transporter which has pH-dependent electrogenic transport activity for alanine and glycine but not for proline. Plays a role in positive regulation of growth by directly or indirectly modulating the effects of the TOR signaling pathway. Required in a cell- autonomous manner for dendrite growth in neurons with large dendrite arbors. (471 aa)    
Predicted Functional Partners:
mab-21
Protein mab-21; Belongs to the mab-21 family.
      
 0.666
JhI-21
Juvenile hormone Inducible-21, isoform A; L-amino acid transmembrane transporter activity. It is involved in the biological process described with: cellular response to leucine; defense response to fungus; L-leucine import across plasma membrane; positive regulation of insulin secretion; carbohydrate homeostasis.
   
  
 0.516
RagA-B
Ras-related GTP binding A/B (RagA-B) encodes a Ras family GTPase that forms a heterodimer with the product of RagC-D. The heterodimer localizes on the lysosome surface and functions to relay amino acid signals to activate the product of Tor by recruiting it to the lysosome.
   
 
 0.499
RagC-D
Protein heterodimerization activity; GTP binding; GTPase activity. It is involved in the biological process described with: regulation of autophagy; positive regulation of TOR signaling; cellular response to starvation; positive regulation of TORC1 signaling; cellular response to amino acid stimulus.
    
 
 0.486
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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