Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mRRF1Mitochondrial ribosome recycling factor 1; Ribosomal large subunit binding. It is involved in the biological process described with: mitochondrial translation; translation. (254 aa)    
Predicted Functional Partners:
mEFTs
Mitochondrial translation elongation factor Ts (mEFTs) encodes a protein predicted to function within mitochondria to recharge the products of mEFTu1 and mEFTu2 with GTP during the elongation phase of mRNA translation; Belongs to the EF-Ts family.
  
 
 0.996
pix
Pixie, isoform A; Pixie (pix) encodes ABCE1, which is an ATPase that functions as a translation recycling factor. It is required for the assembly of complexes involved in translation initiation, and plays a role in the regulation of cellular and organismal growth.
      
 0.980
mRpL17
Mitochondrial ribosomal protein L17, isoform A; Structural constituent of ribosome. It is involved in the biological process described with: translation; mitochondrial translation.
  
 
 0.953
mRpS2
Mitochondrial ribosomal protein S2; Structural constituent of ribosome. It is involved in the biological process described with: translation; mitochondrial translation.
  
 
 0.952
mRpL20
Mitochondrial ribosomal protein L20; rRNA binding; structural constituent of ribosome. It is involved in the biological process described with: mitochondrial translation; translation; ribosomal large subunit assembly; Belongs to the bacterial ribosomal protein bL20 family.
  
 
 0.947
mRRF2
Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
   
  
 0.935
mRpL16
Mitochondrial ribosomal protein L16, isoform A; Structural constituent of ribosome; rRNA binding. It is involved in the biological process described with: mitochondrial translation.
   
 
 0.934
sta
40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Required during oogenesis and imaginal development. Belongs to the universal ribosomal protein uS2 family.
  
 
 0.930
mEFG1
Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity). Essential during development as it acts as a retrograde signal from mitocho [...]
  
 
 0.928
mRpL32
39S ribosomal protein L32, mitochondrial; Structural constituent of ribosome. It is involved in the biological process described with: translation; mitochondrial translation.
  
 
 0.927
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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