STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG4461IP01061p; Unfolded protein binding. It is involved in the biological process described with: response to heat; chaperone-mediated protein folding; Belongs to the small heat shock protein (HSP20) family. (200 aa)    
Predicted Functional Partners:
CG13133
IP07647p; Unfolded protein binding. It is involved in the biological process described with: chaperone-mediated protein folding; Belongs to the small heat shock protein (HSP20) family.
   
0.888
Hsp70Ab
Heat-shock-protein-70Ab (Hsp70Ab) encodes a protein involved in response to heat shock and hypoxia.
   
 0.629
CG10359
Uncharacterized protein, isoform E; G protein-coupled receptor binding; chitin binding. It is involved in the biological process described with: G protein-coupled receptor signaling pathway.
      
 0.603
Hsp26
Heat shock protein 26 (Hsp26) encodes a protein involved in protein folding. It contributes to lifespan determination and the response to cold and heat.
  
 
0.594
CG7409
GEO11409p1; Unfolded protein binding. It is involved in the biological process described with: protein refolding; response to heat; chaperone-mediated protein folding; Belongs to the small heat shock protein (HSP20) family.
  
 
0.591
Hsp68
Heat shock protein 68 (Hsp68) encodes a protein involved in lifespan determination and response to heat shock and starvation.
   
 0.590
Hsp83
Heat shock protein 83; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Together with Hop and piwi, mediates canalization, also known as develop [...]
   
 0.578
Hsp23
Heat shock protein 23 (Hsp23) encodes a protein involved in protein folding. It contributes to the response to cold, heat and hypoxia.
  
 
0.574
Hsp67Bc
Heat shock gene 67Bc (Hsp67Bc) encodes a small heat shock protein (hsp) that binds to the product encoded by stv to regulate protein lipidation. The product of Hsp67Bc also induces the phosphorylation of eIF2alpha protein and stimulates autophagy, thereby facilitating the clearance of misfolded proteins. Hsp67Bc expression can be regulated by the product of pcm.
  
  
0.572
Hsf
Heat shock factor protein; DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked.
    
 0.569
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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