node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG42322 | Tsp66E | FBpp0311440 | FBpp0076235 | Uncharacterized protein, isoform N. | Tetraspanin 66E (Tsp66E) encodes a tetraspanin, which spans the membrane four times. When the products of both Tsp66E and Tsp74F are removed, this results in defects in actin polarization, endocytosis, and distribution of the integrin subunit encoded by if during oogenesis. | 0.836 |
CG42322 | beat-VII | FBpp0311440 | FBpp0288767 | Uncharacterized protein, isoform N. | Beaten path VII; It is involved in the biological process described with: heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules. | 0.836 |
CG42322 | dpr8 | FBpp0311440 | FBpp0073730 | Uncharacterized protein, isoform N. | Defective proboscis extension response 8, isoform A; It is involved in the biological process described with: synapse organization; sensory perception of chemical stimulus. | 0.637 |
CG42322 | osy | FBpp0311440 | FBpp0311936 | Uncharacterized protein, isoform N. | RE14039p; ATP binding; ATPase activity. It is involved in the biological process described with: transmembrane transport. | 0.667 |
Spase12 | SrpRbeta | FBpp0084801 | FBpp0306023 | Signal peptidase complex subunit 1; Microsomal signal peptidase is a membrane-bound endoproteinase that removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. | Signal recognition particle receptor beta (SrpRbeta) encodes a protein that contributes to cuticle secretion by epidermal cells. | 0.645 |
Spase12 | Tsp66E | FBpp0084801 | FBpp0076235 | Signal peptidase complex subunit 1; Microsomal signal peptidase is a membrane-bound endoproteinase that removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. | Tetraspanin 66E (Tsp66E) encodes a tetraspanin, which spans the membrane four times. When the products of both Tsp66E and Tsp74F are removed, this results in defects in actin polarization, endocytosis, and distribution of the integrin subunit encoded by if during oogenesis. | 0.667 |
SrpRbeta | Spase12 | FBpp0306023 | FBpp0084801 | Signal recognition particle receptor beta (SrpRbeta) encodes a protein that contributes to cuticle secretion by epidermal cells. | Signal peptidase complex subunit 1; Microsomal signal peptidase is a membrane-bound endoproteinase that removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. | 0.645 |
SrpRbeta | Tsp66E | FBpp0306023 | FBpp0076235 | Signal recognition particle receptor beta (SrpRbeta) encodes a protein that contributes to cuticle secretion by epidermal cells. | Tetraspanin 66E (Tsp66E) encodes a tetraspanin, which spans the membrane four times. When the products of both Tsp66E and Tsp74F are removed, this results in defects in actin polarization, endocytosis, and distribution of the integrin subunit encoded by if during oogenesis. | 0.602 |
TSG101 | Tsp66E | FBpp0075088 | FBpp0076235 | Tumor susceptibility gene 101 (TSG101) encodes an ESCRT-I complex component that acts as an adapter for membrane rearrangements operated by ESCRT-III. Its roles include endosomal sorting of ubiquitinated cargoes, which is important for signaling regulation, cytokinesis, and budding of viruses and exovesicles. | Tetraspanin 66E (Tsp66E) encodes a tetraspanin, which spans the membrane four times. When the products of both Tsp66E and Tsp74F are removed, this results in defects in actin polarization, endocytosis, and distribution of the integrin subunit encoded by if during oogenesis. | 0.563 |
Tsp5D | Tsp66E | FBpp0303596 | FBpp0076235 | Tetraspanin. | Tetraspanin 66E (Tsp66E) encodes a tetraspanin, which spans the membrane four times. When the products of both Tsp66E and Tsp74F are removed, this results in defects in actin polarization, endocytosis, and distribution of the integrin subunit encoded by if during oogenesis. | 0.540 |
Tsp5D | if | FBpp0303596 | FBpp0290568 | Tetraspanin. | Integrin alpha-PS2 heavy chain; Inflated (if) encodes one of five fly integrin alpha subunits, and when in a heterodimer with an integrin beta subunit makes a receptor for extracellular matrix proteins containing an RGD motif, such as those encoded by Tig, wb laminin and Tsp. It is required in numerous tissues for cell migration and adhesion between cell layers. | 0.427 |
Tsp5D | mew | FBpp0303596 | FBpp0309167 | Tetraspanin. | Integrin alpha-PS1 heavy chain; Multiple edematous wings (mew) encodes one of 5 fly integrin alpha subunits, and when in a heterodimer with an integrin beta subunit makes a receptor for the extracellular matrix protein laminin. It is required in numerous tissues for cell migration, adhesion between cell layers, and cell differentiation. | 0.523 |
Tsp66E | CG42322 | FBpp0076235 | FBpp0311440 | Tetraspanin 66E (Tsp66E) encodes a tetraspanin, which spans the membrane four times. When the products of both Tsp66E and Tsp74F are removed, this results in defects in actin polarization, endocytosis, and distribution of the integrin subunit encoded by if during oogenesis. | Uncharacterized protein, isoform N. | 0.836 |
Tsp66E | Spase12 | FBpp0076235 | FBpp0084801 | Tetraspanin 66E (Tsp66E) encodes a tetraspanin, which spans the membrane four times. When the products of both Tsp66E and Tsp74F are removed, this results in defects in actin polarization, endocytosis, and distribution of the integrin subunit encoded by if during oogenesis. | Signal peptidase complex subunit 1; Microsomal signal peptidase is a membrane-bound endoproteinase that removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. | 0.667 |
Tsp66E | SrpRbeta | FBpp0076235 | FBpp0306023 | Tetraspanin 66E (Tsp66E) encodes a tetraspanin, which spans the membrane four times. When the products of both Tsp66E and Tsp74F are removed, this results in defects in actin polarization, endocytosis, and distribution of the integrin subunit encoded by if during oogenesis. | Signal recognition particle receptor beta (SrpRbeta) encodes a protein that contributes to cuticle secretion by epidermal cells. | 0.602 |
Tsp66E | TSG101 | FBpp0076235 | FBpp0075088 | Tetraspanin 66E (Tsp66E) encodes a tetraspanin, which spans the membrane four times. When the products of both Tsp66E and Tsp74F are removed, this results in defects in actin polarization, endocytosis, and distribution of the integrin subunit encoded by if during oogenesis. | Tumor susceptibility gene 101 (TSG101) encodes an ESCRT-I complex component that acts as an adapter for membrane rearrangements operated by ESCRT-III. Its roles include endosomal sorting of ubiquitinated cargoes, which is important for signaling regulation, cytokinesis, and budding of viruses and exovesicles. | 0.563 |
Tsp66E | Tsp5D | FBpp0076235 | FBpp0303596 | Tetraspanin 66E (Tsp66E) encodes a tetraspanin, which spans the membrane four times. When the products of both Tsp66E and Tsp74F are removed, this results in defects in actin polarization, endocytosis, and distribution of the integrin subunit encoded by if during oogenesis. | Tetraspanin. | 0.540 |
Tsp66E | beat-VII | FBpp0076235 | FBpp0288767 | Tetraspanin 66E (Tsp66E) encodes a tetraspanin, which spans the membrane four times. When the products of both Tsp66E and Tsp74F are removed, this results in defects in actin polarization, endocytosis, and distribution of the integrin subunit encoded by if during oogenesis. | Beaten path VII; It is involved in the biological process described with: heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules. | 0.696 |
Tsp66E | dpr8 | FBpp0076235 | FBpp0073730 | Tetraspanin 66E (Tsp66E) encodes a tetraspanin, which spans the membrane four times. When the products of both Tsp66E and Tsp74F are removed, this results in defects in actin polarization, endocytosis, and distribution of the integrin subunit encoded by if during oogenesis. | Defective proboscis extension response 8, isoform A; It is involved in the biological process described with: synapse organization; sensory perception of chemical stimulus. | 0.532 |
Tsp66E | if | FBpp0076235 | FBpp0290568 | Tetraspanin 66E (Tsp66E) encodes a tetraspanin, which spans the membrane four times. When the products of both Tsp66E and Tsp74F are removed, this results in defects in actin polarization, endocytosis, and distribution of the integrin subunit encoded by if during oogenesis. | Integrin alpha-PS2 heavy chain; Inflated (if) encodes one of five fly integrin alpha subunits, and when in a heterodimer with an integrin beta subunit makes a receptor for extracellular matrix proteins containing an RGD motif, such as those encoded by Tig, wb laminin and Tsp. It is required in numerous tissues for cell migration and adhesion between cell layers. | 0.543 |