Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
CG5087RE40614p; Ubiquitin-protein transferase activity; ubiquitin conjugating enzyme activity. It is involved in the biological process described with: ubiquitin-dependent protein catabolic process; protein polyubiquitination; protein ubiquitination. (1078 aa)    
Predicted Functional Partners:
CG5280
UPF0193 protein EVG1 homolog; Belongs to the UPF0193 (EVG1) family.
      
 0.813
Gart
Trifunctional purine biosynthetic protein adenosine-3; GART trifunctional enzyme (Gart) encodes a multifunctional enzyme that exhibits phosphoribosylamine-glycine ligase, phosphoribosylformylglycinamidine cyclo-ligase and phosphoribosylglycinamide formyltransferase activities; In the N-terminal section; belongs to the GARS family. In the C-terminal section; belongs to the GART family.
      
 0.752
CG2924
LD28546p; Ubiquitin-protein transferase activity; ubiquitin conjugating enzyme activity. It is involved in the biological process described with: protein K48-linked ubiquitination; protein polyubiquitination.
   
  
 0.658
CG5194
Uncharacterized protein, isoform A.
      
 0.655
CG33704
GEO11111p1.
      
 0.654
CG34115
GEO11031p1.
      
 0.654
CG15650
FI22632p1.
      
 0.652
CG4911
LD04326p; It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process.
   
  
 0.651
CG10543
Uncharacterized protein, isoform F; RNA polymerase II regulatory region sequence-specific DNA binding; sequence-specific DNA binding; zinc ion binding; DNA-binding transcription factor activity, RNA polymerase II-specific. It is involved in the biological process described with: regulation of transcription by RNA polymerase II; gravitaxis.
   
  
 0.622
CG5823
HL05730p; Ubiquitin-protein transferase activity; ubiquitin conjugating enzyme activity. It is involved in the biological process described with: protein ubiquitination; ubiquitin-dependent ERAD pathway; protein polyubiquitination.
   
  
 0.620
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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