STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ArgkKinase activity; arginine kinase activity; creatine kinase activity. It is involved in the biological process described with: phosphocreatine biosynthetic process; phosphorylation; Belongs to the ATP:guanido phosphotransferase family. (562 aa)    
Predicted Functional Partners:
arg
Arginase (arg) encodes an enzyme that converts arginine into ornithine. Lack of arg produces a developmental embryonic delay.
     
 0.921
CG4546
GH24918p; Kinase activity; creatine kinase activity. It is involved in the biological process described with: multicellular organism reproduction; phosphocreatine biosynthetic process; Belongs to the ATP:guanido phosphotransferase family.
  
  
 
0.906
CG5144
Uncharacterized protein; Kinase activity; creatine kinase activity. It is involved in the biological process described with: phosphocreatine biosynthetic process; Belongs to the ATP:guanido phosphotransferase family.
  
  
0.902
Nos
Nitric oxide synthase; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. Truncated isoforms (isoform 3- isoform 6) are able to form intracellular complexes with the full- length protein and serve as dominant negative inhibitors of the enzyme activity; Belongs to the NOS family.
     
  0.900
CG34228
HDC05827.
   
  
 0.854
CG7378
Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.
   
    0.851
CG32591
FI08446p.
   
    0.849
lost
LD30155p; Lost (lost) encodes a protein that interacts with the RNA-binding protein encoded by rump for posterior localization of mRNAs by diffusion/entrapment during late stages of oogenesis. The identification of the product of lost in various RNP complexes suggests a broad role in RNA metabolism.
   
    0.848
CG14391
FI08238p.
   
    0.847
Nipsnap
Protein NipSnap; Belongs to the NipSnap family.
   
    0.845
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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