STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG5280UPF0193 protein EVG1 homolog; Belongs to the UPF0193 (EVG1) family. (250 aa)    
Predicted Functional Partners:
CG5087
RE40614p; Ubiquitin-protein transferase activity; ubiquitin conjugating enzyme activity. It is involved in the biological process described with: ubiquitin-dependent protein catabolic process; protein polyubiquitination; protein ubiquitination.
      
 0.793
dtr
Dynein assembly factor 1, axonemal homolog; Cilium-specific protein required for cilia structures. Belongs to the DNAAF1 family.
   
    0.694
CG31294
TPR_REGION domain-containing protein.
   
    0.565
CG6980
GH10293p.
   
    0.535
CG34274
IP18157p.
   
    0.535
Dnali1
Putative inner dynein arm light chain, axonemal; May play a dynamic role in flagellar motility.
   
    0.516
bcd
Homeotic protein bicoid; Segment polarity protein that provides positional cues for the development of head and thoracic segments. Regulates the expression of zygotic genes, possibly through its homeodomain, and inhibits the activity of other maternal gene products. May also bind RNA. Interacts with Bin1 to repress transcription of bicoid target genes in the anterior tip of the embryo; a process known as retraction.
   
    0.507
CG34297
RT07743p; Molecular adaptor activity. It is involved in the biological process described with: response to heat.
   
    0.507
CG7251
CG7251-PA.
   
    0.435
CG9588
26S proteasome non-ATPase regulatory subunit 9; Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the PA700/19S regulatory complex (RC).
      
 0.422
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.