STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GalkGalactokinase, isoform A; Galactokinase (Galk) encodes a protein involved in galactose metabolism that regulates calcineurin-induced cardiac enlargement. (490 aa)    
Predicted Functional Partners:
Gale
UDP-glucose 4-epimerase; Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP- Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconvers [...]
  
 
 0.999
Galt
Galactose-1-phosphate uridylyltransferase (Galt) encodes an enzyme that contributes to galactose homeostasis and adult locomotory behavior.
 
 0.999
UGP
UTP--glucose-1-phosphate uridylyltransferase; UGP (UGP) encodes an enzyme involved in hyperoxia response.
  
  
 0.888
CG3609
LD06553p; Oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process.
  
 
 0.825
CG3597
Uncharacterized protein, isoform B; Oxidoreductase activity.
  
 
 0.812
CG13280
Uncharacterized protein, isoform A; Oxidoreductase activity.
  
 
 0.794
sgl
UDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate and heparan sulfate. Required for wingless signaling in different tissues; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
  
  
 0.765
CG10467
Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.
  
 
 0.762
CG32444
Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.
  
 
 0.758
Taldo
Probable transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
  
  
 0.751
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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