Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Pex7Peroxin 7, isoform A; Peroxisome matrix targeting signal-2 binding. It is involved in the biological process described with: peroxisome organization; protein import into peroxisome matrix. (339 aa)    
Predicted Functional Partners:
Pex5
Peroxin 5, isoform A; Peroxisome matrix targeting signal-1 binding. It is involved in the biological process described with: protein import into peroxisome matrix, docking; response to anesthetic; peroxisome organization.
    
 0.999
Pex13
Peroxin 13 (Pex13) encodes a peroxisome protein important for sperm development.
   
 0.998
Pex14
Peroxin 14; Signaling receptor binding. It is involved in the biological process described with: protein targeting to peroxisome; peroxisome organization; protein import into peroxisome matrix, docking.
    
 0.995
Pex10
Peroxin 10 (Pex10) encodes a peroxisome protein important for sperm development.
     
 0.989
ADPS
Alkyldihydroxyacetonephosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids; Belongs to the FAD-binding oxidoreductase/transferase type 4 family.
   
 
 0.987
Pex12
Peroxin 12 (Pex12) encodes a peroxisome protein important for sperm development; Belongs to the pex2/pex10/pex12 family.
     
 0.984
Pex6
Peroxin 6, isoform D; ATP binding; ATPase activity. It is involved in the biological process described with: peroxisome organization; protein import into peroxisome matrix; protein targeting to peroxisome.
      
 0.975
Pex19
Peroxin 19, isoform A; Peroxisome membrane targeting sequence binding. It is involved in the biological process described with: nervous system development; protein import into peroxisome membrane; peroxisome organization.
      
 0.961
Pex16
Peroxin 16 (Pex16) encodes a protein involved in peroxisome organization, spermatocyte division, and fatty acid catabolism.
      
 0.954
Pex11
Peroxin 11; It is involved in the biological process described with: regulation of peroxisome size; peroxisome fission; peroxisome organization.
   
  
 0.952
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.