Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CG7083UPF0183 protein CG7083; It is involved in the biological process described with: Golgi to plasma membrane protein transport; Belongs to the UPF0183 family. (438 aa)    
Predicted Functional Partners:
rudhira
Breast carcinoma-amplified sequence 3 homolog; Rudhira (rudhira) is expressed in nephrocytes and encodes a protein that regulates macromolecular uptake and clearance by nephrocytes to maintain tissue homeostasis; Belongs to the BCAS3 family.
   
 
 0.973
mRpL48
Mitochondrial ribosomal protein L48, isoform A; Structural constituent of ribosome. It is involved in the biological process described with: mitochondrial translation.
      
 0.824
NTPase
NTPase, isoform F; Uridine-diphosphatase activity; guanosine-diphosphatase activity; Belongs to the GDA1/CD39 NTPase family.
      
 0.755
Pomp
GEO05038p1; It is involved in the biological process described with: proteasome assembly; proteasome-mediated ubiquitin-dependent protein catabolic process; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; proteolysis.
    
   0.676
RhoGAP68F
Rho GTPase activating protein at 68F (RhoGAP68F) encodes a GTPase activating protein acting upon small Rho-family GTPases involved in epithelial morphogenesis. It localizes to Rab4 recycling endosomes, forms a complex with the product of Rab4 and modulates the transport of Rab4 recycling endosomes back to the cell surface.
   
  
 0.672
DNApol-alpha50
DNA primase small subunit; Catalytic subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. During the S phase of the cell cycle, the DNA polymerase alpha complex (composed of a catalytic subunit DNApol-alpha180/DNApolA1, an accessory subunit DNApol-alpha73/DNApolA2 and two primase subunits, the catalytic subunit DNApol-alpha50/DNAprim1 and the regulatory subunit DNApol- alpha60/DNAprim2) is recruited to DNA at the replicative forks (By [...]
 
      0.634
Pex2
Peroxin 2 (Pex2) encodes a peroxisome protein important for sperm development.
 
 
    0.632
CG31223
LD44220p.
      
 0.600
Nach
Sodium channel protein Nach; Nach (Nach) encodes a predicted member of the Degenerin/Epithelial Sodium Channel family of proteins. It is mainly expressed in the tracheal system and functions in liquid clearance during tracheal development; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
      
 0.598
IntS1
Integrator complex subunit 1; Component of the Integrator complex, a complex involved in the transcription of small nuclear RNAs (snRNA) and their 3'-box- dependent processing. Involved in the 3'-end processing of the U7 snRNA, and also the spliceosomal snRNAs U1, U2, U4 and U5. Required for the normal expression of the Integrator complex component IntS12. May mediate recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (By similarity).
      
 0.597
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.