node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG11674 | Pxt | FBpp0073743 | FBpp0082932 | LD24340p. | Chorion peroxidase; Peroxinectin-like (Pxt) encodes a cycloxygenase-like enzyme that contributes to the synthesis of prostaglandins. Prostaglandins activate G protein-coupled receptor signaling. Its roles include oogenesis, sperm individualization, morphogenesis, nucleolar structure, temporal control of gene expression, and regulation of gene amplification; Belongs to the peroxidase family. XPO subfamily. | 0.776 |
CG11674 | alphaTub67C | FBpp0073743 | FBpp0076122 | LD24340p. | Tubulin alpha-4 chain; alpha-Tubulin at 67C (alphaTub67C) encodes a protein that form heterodimers with beta-tubulins to polymerise and form microtubules. Tubulin molecules containing the product of alphaTub67C are essential for fast growth of the microtubules during the initial cleavage divisions of embryogenesis. | 0.850 |
CG11674 | dhd | FBpp0073743 | FBpp0311766 | LD24340p. | Thioredoxin-1; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. As a reducing substrate of peroxiredoxin 1, thioredoxin 2 is preferred over thioredoxin 1. Required for female meiosis and early embryonic development. | 0.840 |
CG11674 | gnu | FBpp0073743 | FBpp0075447 | LD24340p. | CG5272 protein; Giant nuclei (gnu) encodes a regulatory subunit of the PNG kinase complex, which regulates the levels of the protein encoded by CycB. Members of this complex are required maternally for the normal nuclear divisions of the syncytial embryo. | 0.845 |
CG11674 | mtrm | FBpp0073743 | FBpp0076340 | LD24340p. | Protein matrimony; Polo kinase inhibitor required to maintain G2 arrest in the meiotic cell cycle in females. Holds heterochromatically paired homologs together from the end of pachytene until metaphase I. Haploinsufficient locus for homologous achiasmate segregation and may be required for the maintenance of heterochromatic pairings. | 0.909 |
CG11674 | osk | FBpp0073743 | FBpp0081435 | LD24340p. | Maternal effect protein oskar; Organizes the germ plasm and directs localization of the posterior determinant nanos. Oskar protein is required to keep nos RNA and staufen protein at the posterior pole. | 0.883 |
CG11674 | otu | FBpp0073743 | FBpp0089325 | LD24340p. | Protein ovarian tumor locus; Essential for female fertility; germ cell division and differentiation. | 0.838 |
CG11674 | wisp | FBpp0073743 | FBpp0309611 | LD24340p. | Poly(A) RNA polymerase gld-2 homolog B; Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific maternal RNAs (bcd, Tl, and tor), forming a poly(A) tail, during late oogenesis and early embryogenesis. In contrast to the canonical nuclear poly(A) RNA polymerase, it only adds poly(A) to selected cytoplasmic mRNAs. Required for localization of mRNAs to both poles of the egg, to recruit or maintain known centrosomal proteins with two types of microtubule organizing centers (MTOCs): the central MTOC that forms between the meiosis II tandem spindles and [...] | 0.791 |
Pxt | CG11674 | FBpp0082932 | FBpp0073743 | Chorion peroxidase; Peroxinectin-like (Pxt) encodes a cycloxygenase-like enzyme that contributes to the synthesis of prostaglandins. Prostaglandins activate G protein-coupled receptor signaling. Its roles include oogenesis, sperm individualization, morphogenesis, nucleolar structure, temporal control of gene expression, and regulation of gene amplification; Belongs to the peroxidase family. XPO subfamily. | LD24340p. | 0.776 |
Pxt | alphaTub67C | FBpp0082932 | FBpp0076122 | Chorion peroxidase; Peroxinectin-like (Pxt) encodes a cycloxygenase-like enzyme that contributes to the synthesis of prostaglandins. Prostaglandins activate G protein-coupled receptor signaling. Its roles include oogenesis, sperm individualization, morphogenesis, nucleolar structure, temporal control of gene expression, and regulation of gene amplification; Belongs to the peroxidase family. XPO subfamily. | Tubulin alpha-4 chain; alpha-Tubulin at 67C (alphaTub67C) encodes a protein that form heterodimers with beta-tubulins to polymerise and form microtubules. Tubulin molecules containing the product of alphaTub67C are essential for fast growth of the microtubules during the initial cleavage divisions of embryogenesis. | 0.853 |
Pxt | dhd | FBpp0082932 | FBpp0311766 | Chorion peroxidase; Peroxinectin-like (Pxt) encodes a cycloxygenase-like enzyme that contributes to the synthesis of prostaglandins. Prostaglandins activate G protein-coupled receptor signaling. Its roles include oogenesis, sperm individualization, morphogenesis, nucleolar structure, temporal control of gene expression, and regulation of gene amplification; Belongs to the peroxidase family. XPO subfamily. | Thioredoxin-1; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. As a reducing substrate of peroxiredoxin 1, thioredoxin 2 is preferred over thioredoxin 1. Required for female meiosis and early embryonic development. | 0.858 |
Pxt | gnu | FBpp0082932 | FBpp0075447 | Chorion peroxidase; Peroxinectin-like (Pxt) encodes a cycloxygenase-like enzyme that contributes to the synthesis of prostaglandins. Prostaglandins activate G protein-coupled receptor signaling. Its roles include oogenesis, sperm individualization, morphogenesis, nucleolar structure, temporal control of gene expression, and regulation of gene amplification; Belongs to the peroxidase family. XPO subfamily. | CG5272 protein; Giant nuclei (gnu) encodes a regulatory subunit of the PNG kinase complex, which regulates the levels of the protein encoded by CycB. Members of this complex are required maternally for the normal nuclear divisions of the syncytial embryo. | 0.844 |
Pxt | gwl | FBpp0082932 | FBpp0083089 | Chorion peroxidase; Peroxinectin-like (Pxt) encodes a cycloxygenase-like enzyme that contributes to the synthesis of prostaglandins. Prostaglandins activate G protein-coupled receptor signaling. Its roles include oogenesis, sperm individualization, morphogenesis, nucleolar structure, temporal control of gene expression, and regulation of gene amplification; Belongs to the peroxidase family. XPO subfamily. | Greatwall, isoform A; Greatwall (gwl) encodes a kinase required for mitosis and female meiosis. It phosphorylates the product of endos, which then acts as a stoichiometric inhibitor of the PP2A B-type adaptor subunit encoded by tws. | 0.580 |
Pxt | mtrm | FBpp0082932 | FBpp0076340 | Chorion peroxidase; Peroxinectin-like (Pxt) encodes a cycloxygenase-like enzyme that contributes to the synthesis of prostaglandins. Prostaglandins activate G protein-coupled receptor signaling. Its roles include oogenesis, sperm individualization, morphogenesis, nucleolar structure, temporal control of gene expression, and regulation of gene amplification; Belongs to the peroxidase family. XPO subfamily. | Protein matrimony; Polo kinase inhibitor required to maintain G2 arrest in the meiotic cell cycle in females. Holds heterochromatically paired homologs together from the end of pachytene until metaphase I. Haploinsufficient locus for homologous achiasmate segregation and may be required for the maintenance of heterochromatic pairings. | 0.855 |
Pxt | osk | FBpp0082932 | FBpp0081435 | Chorion peroxidase; Peroxinectin-like (Pxt) encodes a cycloxygenase-like enzyme that contributes to the synthesis of prostaglandins. Prostaglandins activate G protein-coupled receptor signaling. Its roles include oogenesis, sperm individualization, morphogenesis, nucleolar structure, temporal control of gene expression, and regulation of gene amplification; Belongs to the peroxidase family. XPO subfamily. | Maternal effect protein oskar; Organizes the germ plasm and directs localization of the posterior determinant nanos. Oskar protein is required to keep nos RNA and staufen protein at the posterior pole. | 0.985 |
Pxt | otu | FBpp0082932 | FBpp0089325 | Chorion peroxidase; Peroxinectin-like (Pxt) encodes a cycloxygenase-like enzyme that contributes to the synthesis of prostaglandins. Prostaglandins activate G protein-coupled receptor signaling. Its roles include oogenesis, sperm individualization, morphogenesis, nucleolar structure, temporal control of gene expression, and regulation of gene amplification; Belongs to the peroxidase family. XPO subfamily. | Protein ovarian tumor locus; Essential for female fertility; germ cell division and differentiation. | 0.848 |
Pxt | wisp | FBpp0082932 | FBpp0309611 | Chorion peroxidase; Peroxinectin-like (Pxt) encodes a cycloxygenase-like enzyme that contributes to the synthesis of prostaglandins. Prostaglandins activate G protein-coupled receptor signaling. Its roles include oogenesis, sperm individualization, morphogenesis, nucleolar structure, temporal control of gene expression, and regulation of gene amplification; Belongs to the peroxidase family. XPO subfamily. | Poly(A) RNA polymerase gld-2 homolog B; Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific maternal RNAs (bcd, Tl, and tor), forming a poly(A) tail, during late oogenesis and early embryogenesis. In contrast to the canonical nuclear poly(A) RNA polymerase, it only adds poly(A) to selected cytoplasmic mRNAs. Required for localization of mRNAs to both poles of the egg, to recruit or maintain known centrosomal proteins with two types of microtubule organizing centers (MTOCs): the central MTOC that forms between the meiosis II tandem spindles and [...] | 0.834 |
alphaTub67C | CG11674 | FBpp0076122 | FBpp0073743 | Tubulin alpha-4 chain; alpha-Tubulin at 67C (alphaTub67C) encodes a protein that form heterodimers with beta-tubulins to polymerise and form microtubules. Tubulin molecules containing the product of alphaTub67C are essential for fast growth of the microtubules during the initial cleavage divisions of embryogenesis. | LD24340p. | 0.850 |
alphaTub67C | Pxt | FBpp0076122 | FBpp0082932 | Tubulin alpha-4 chain; alpha-Tubulin at 67C (alphaTub67C) encodes a protein that form heterodimers with beta-tubulins to polymerise and form microtubules. Tubulin molecules containing the product of alphaTub67C are essential for fast growth of the microtubules during the initial cleavage divisions of embryogenesis. | Chorion peroxidase; Peroxinectin-like (Pxt) encodes a cycloxygenase-like enzyme that contributes to the synthesis of prostaglandins. Prostaglandins activate G protein-coupled receptor signaling. Its roles include oogenesis, sperm individualization, morphogenesis, nucleolar structure, temporal control of gene expression, and regulation of gene amplification; Belongs to the peroxidase family. XPO subfamily. | 0.853 |
alphaTub67C | dhd | FBpp0076122 | FBpp0311766 | Tubulin alpha-4 chain; alpha-Tubulin at 67C (alphaTub67C) encodes a protein that form heterodimers with beta-tubulins to polymerise and form microtubules. Tubulin molecules containing the product of alphaTub67C are essential for fast growth of the microtubules during the initial cleavage divisions of embryogenesis. | Thioredoxin-1; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. As a reducing substrate of peroxiredoxin 1, thioredoxin 2 is preferred over thioredoxin 1. Required for female meiosis and early embryonic development. | 0.855 |