STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pus7Pseudouridine synthase activity; RNA binding. It is involved in the biological process described with: pseudouridine synthesis. (734 aa)    
Predicted Functional Partners:
Pus1
Pseudouridine synthase activity; RNA binding. It is involved in the biological process described with: tRNA pseudouridine synthesis; mRNA pseudouridine synthesis.
   
 
 0.992
Nsun2
tRNA (cytosine(34)-C(5))-methyltransferase; RNA methyltransferase that methylates tRNAs. Methylates cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA(Leu)(CAA) precursors. Required for short-term memory.
   
 
 0.969
CG3709
Putative tRNA pseudouridine synthase Pus10; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase Pus10 family.
   
  
 0.957
RluA-2
Pseudouridine synthase activity; RNA binding. It is involved in the biological process described with: defense response to Gram-negative bacterium; positive regulation of innate immune response; enzyme-directed rRNA pseudouridine synthesis.
   
 
 0.953
RluA-1
RluA pseudouridine synthase 1 (RluA-1) encodes a pseudouridine synthase, an enzyme catalyzing the formation of the most abundant nucleoside modification of RNA, pseudouridine.
    
 
 0.952
CG14100
rRNA methyltransferase 3, mitochondrial; S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 1580 (Gm1580) in the mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a conserved modification in the peptidyl transferase domain of the mtLSU rRNA.
   
 
 0.912
CG1234
Nucleolar complex protein 3 homolog; Chromatin binding.
   
   0.907
mRpL15
Mitochondrial ribosomal protein L15; Structural constituent of ribosome. It is involved in the biological process described with: translation; mitochondrial translation.
   
   0.906
CG12123
GH02722p.
    
 
 0.900
mRpL13
39S ribosomal protein L13, mitochondrial; mRNA binding; structural constituent of ribosome. It is involved in the biological process described with: negative regulation of translation; mitochondrial translation; translation; Belongs to the universal ribosomal protein uL13 family.
   
   0.899
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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