Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
GstO3Glutathione S-transferase omega class; Glutathione S transferase O3 (GstO3) encodes a transferase involved in glutathione metabolism; Belongs to the GST superfamily. (241 aa)    
Predicted Functional Partners:
GstT4
Glutathione peroxidase activity; glutathione transferase activity. It is involved in the biological process described with: glutathione metabolic process; Belongs to the GST superfamily.
   
 
 0.863
GstO1
Glutathione S-transferase omega class; Glutathione S transferase O1 (GstO1) encodes a transferase involved in glutathione metabolism; Belongs to the GST superfamily.
  
0.859
GstD1
Glutathione S-transferase D1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has DDT dehydrochlorinase activity. May be involved in detoxification.
   
 
 0.835
GstE12
Glutathione S transferase E12 (GstE12) encodes an enzyme involved in glutathione metabolism; Belongs to the GST superfamily.
   
 0.810
GstT3
Glutathione S transferase T3 (GstT3) encodes an enzyme involved in glutathione metabolic processes; Belongs to the GST superfamily.
   
 
 0.804
GstT2
Glutathione S transferase T2 (GstT2) encodes an enzyme involved in glutathione metabolic processes; Belongs to the GST superfamily.
   
 
 0.802
GstE3
Glutathione S transferase E3 (GstE3) encodes an enzyme involved in glutathione metabolic processes.
   
 
 0.798
GstD6
Glutathione S-transferase D6; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. May be involved in detoxification.
     
 0.796
GstD8
Glutathione S transferase D8 (GstD8) encodes an enzyme with broad substrate specificity involved in glutathione metabolism.
   
 
 0.788
GstS1
Glutathione S-transferase S1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. May be involved in the detoxification of metabolites produced during cellular division and morphogenesis.
   
 0.783
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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