STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GstO1Glutathione S-transferase omega class; Glutathione S transferase O1 (GstO1) encodes a transferase involved in glutathione metabolism; Belongs to the GST superfamily. (254 aa)    
Predicted Functional Partners:
GstT2
Glutathione S transferase T2 (GstT2) encodes an enzyme involved in glutathione metabolic processes; Belongs to the GST superfamily.
   
 
 0.933
GstT1
Glutathione S transferase T1 (GstT1) encodes an enzyme involved in glutathione metabolic processes; Belongs to the GST superfamily.
   
 
 0.886
GstE7
Glutathione S transferase E7 (GstE7) encodes a cytosolic enzyme that functions in detoxication. It has high catalytic activity with various isothiocyanates and the toxic environmental pollutants 2,4,6-trinitrotoluene (TNT) and 2,4-dinitrotoluene (DNT).
   
 
 0.870
GstD1
Glutathione S-transferase D1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has DDT dehydrochlorinase activity. May be involved in detoxification.
   
 
 0.849
GstO2
Glutathione S transferase O2 (GstO2) encodes a protein involved in glutathione metabolism; Belongs to the GST superfamily.
  
0.833
GstE4
Glutathione S transferase E4 (GstE4) encodes an enzyme involved in glutathione metabolic processes; Belongs to the GST superfamily.
   
 
 0.832
GstE8
Glutathione transferase activity. It is involved in the biological process described with: glutathione metabolic process.
   
 
 0.831
GstE12
Glutathione S transferase E12 (GstE12) encodes an enzyme involved in glutathione metabolism; Belongs to the GST superfamily.
   
 
 0.830
gfzf
GST-containing FLYWCH zinc-finger protein (gfzf) encodes encodes a glutathione binding protein that is predicted by phylogeny to have glutathione transferase activity; Belongs to the GST superfamily.
   
 0.828
PHGPx
PHGPx (PHGPx) encodes a peroxidase involved in intestinal stem cell homeostasis and the response to endoplasmic reticulum stress.
   
 0.815
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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