Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GstO2Glutathione S transferase O2 (GstO2) encodes a protein involved in glutathione metabolism; Belongs to the GST superfamily. (251 aa)    
Predicted Functional Partners:
GstO1
Glutathione S-transferase omega class; Glutathione S transferase O1 (GstO1) encodes a transferase involved in glutathione metabolism; Belongs to the GST superfamily.
  
0.999
GstT3
Glutathione S transferase T3 (GstT3) encodes an enzyme involved in glutathione metabolic processes; Belongs to the GST superfamily.
   
 
 0.818
GstT1
Glutathione S transferase T1 (GstT1) encodes an enzyme involved in glutathione metabolic processes; Belongs to the GST superfamily.
   
 
 0.812
GstT2
Glutathione S transferase T2 (GstT2) encodes an enzyme involved in glutathione metabolic processes; Belongs to the GST superfamily.
   
 
 0.800
GstO3
Glutathione S-transferase omega class; Glutathione S transferase O3 (GstO3) encodes a transferase involved in glutathione metabolism; Belongs to the GST superfamily.
  
0.779
GstS1
Glutathione S-transferase S1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. May be involved in the detoxification of metabolites produced during cellular division and morphogenesis.
   
 0.769
GstT4
Glutathione peroxidase activity; glutathione transferase activity. It is involved in the biological process described with: glutathione metabolic process; Belongs to the GST superfamily.
   
 
 0.731
GstZ2
Probable maleylacetoacetate isomerase 2; Catalyzes the glutathione dependent oxygenation of dichloroacetic acid to glyoxylic acid in vitro. Has no glutathione thioltransferase activity with 4-hydroxynonenal (4-HNE), adrenochrome, phenethyl isothiocyanate (PEITC), 5-hydroperoxyeicosatetraenoic acid ((5S)-HpETE), prostaglandin A2 (PGA2) or 2-hydroxyethyldisulfide (HED). Belongs to the GST superfamily. Zeta family.
     
 0.718
GstZ1
Probable maleylacetoacetate isomerase 1; Catalyzes the glutathione dependent oxygenation of dichloroacetic acid to glyoxylic acid in vitro. Possesses low glutathione thioltransferase activity toward 4-hydroxynonenal (4-HNE). Has no glutathione thioltransferase activity with adrenochrome, phenethyl isothiocyanate (PEITC), 5-hydroperoxyeicosatetraenoic acid ((5S)-HpETE), prostaglandin A2 (PGA2) or 2-hydroxyethyldisulfide (HED).
   
  
 0.641
Ugt302C1
UDP-glycosyltransferase family 302 member C1; UDP-glycosyltransferase activity; transferase activity, transferring hexosyl groups. It is involved in the biological process described with: UDP-glucose metabolic process.
   
  
 0.624
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.