Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Fs(2)Ket | Kap-alpha1 | FBpp0294037 | FBpp0074650 | Importin subunit beta; Required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins. In Drosophila, may not function as a snRNP import receptor as it does not interact with components of the snRNP complex such as snRNP U1, U2, U4/U6 and Snup. | Importin subunit alpha; Karyopherin alpha1 (Kap-alpha1) encodes a protein that is involved in spermatogenesis and the nuclear import of the product of yki. | 0.985 |
| Fs(2)Ket | Kap-alpha3 | FBpp0294037 | FBpp0081585 | Importin subunit beta; Required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins. In Drosophila, may not function as a snRNP import receptor as it does not interact with components of the snRNP complex such as snRNP U1, U2, U4/U6 and Snup. | Importin subunit alpha; Karyopherin alpha3 (Kap-alpha3) encodes a protein required for the nuclear import of the product of N; Belongs to the importin alpha family. | 0.955 |
| Fs(2)Ket | Karybeta3 | FBpp0294037 | FBpp0078500 | Importin subunit beta; Required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins. In Drosophila, may not function as a snRNP import receptor as it does not interact with components of the snRNP complex such as snRNP U1, U2, U4/U6 and Snup. | Karyopherin beta 3, isoform A; Nuclear localization sequence binding; nuclear import signal receptor activity. It is involved in the biological process described with: protein import into nucleus. | 0.738 |
| Fs(2)Ket | Nup153 | FBpp0294037 | FBpp0309144 | Importin subunit beta; Required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins. In Drosophila, may not function as a snRNP import receptor as it does not interact with components of the snRNP complex such as snRNP U1, U2, U4/U6 and Snup. | Nuclear pore complex protein Nup153; Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC. Essential for the nuclear import of nuclear localization signal (NLS)-containing proteins in a Importin alpha/Importin beta receptor-dependent manner. Required for nuclear import of Mad. Plays a role in chromosomal organization and gene expression regulation; stimulates transcription by promoting the formation of an open chromatin environment. Binds chromatin to nucleopor [...] | 0.966 |
| Fs(2)Ket | Ran | FBpp0294037 | FBpp0073328 | Importin subunit beta; Required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins. In Drosophila, may not function as a snRNP import receptor as it does not interact with components of the snRNP complex such as snRNP U1, U2, U4/U6 and Snup. | GTP-binding nuclear protein Ran; GTPase involved in nucleocytoplasmic transport, participating both to the import and the export from the nucleus of proteins and RNAs. Switches between a cytoplasmic GDP- and a nuclear GTP-bound state by nucleotide exchange and GTP hydrolysis. Nuclear import receptors such as importin beta bind their substrates only in the absence of GTP- bound RAN and release them upon direct interaction with GTP-bound RAN, while export receptors behave in the opposite way. Thereby, RAN controls cargo loading and release by transport receptors in the proper compartment [...] | 0.980 |
| Fs(2)Ket | Tnpo | FBpp0294037 | FBpp0076708 | Importin subunit beta; Required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins. In Drosophila, may not function as a snRNP import receptor as it does not interact with components of the snRNP complex such as snRNP U1, U2, U4/U6 and Snup. | Transportin, isoform A; Transportin (Tnpo) encodes a protein involved in Hh signalling regulation by mediating the import of the transcription factor encoded by ci into the nucleus. | 0.571 |
| Fs(2)Ket | Tnpo-SR | FBpp0294037 | FBpp0307125 | Importin subunit beta; Required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins. In Drosophila, may not function as a snRNP import receptor as it does not interact with components of the snRNP complex such as snRNP U1, U2, U4/U6 and Snup. | Transportin-Serine/Arginine rich (Tnpo-SR) encodes a importin-beta family protein involved in the regulation of mRNA splicing. It contributes to the import into the nucleus of serine/arginine-rich (SR) proteins, which are involved in mRNA splicing. | 0.458 |
| Fs(2)Ket | alphaKap4 | FBpp0294037 | FBpp0076777 | Importin subunit beta; Required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins. In Drosophila, may not function as a snRNP import receptor as it does not interact with components of the snRNP complex such as snRNP U1, U2, U4/U6 and Snup. | Importin subunit alpha; Nuclear import signal receptor activity; nuclear localization sequence binding. It is involved in the biological process described with: proteasome assembly; NLS-bearing protein import into nucleus; Belongs to the importin alpha family. | 0.818 |
| Fs(2)Ket | msk | FBpp0294037 | FBpp0076408 | Importin subunit beta; Required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins. In Drosophila, may not function as a snRNP import receptor as it does not interact with components of the snRNP complex such as snRNP U1, U2, U4/U6 and Snup. | D-Importin 7/RanBP7; Moleskin (msk) encodes an importin that contributes to protein import into the nucleus. It is involved in eye development, muscle attachment and wing cell fate specification. | 0.971 |
| Kap-alpha1 | Fs(2)Ket | FBpp0074650 | FBpp0294037 | Importin subunit alpha; Karyopherin alpha1 (Kap-alpha1) encodes a protein that is involved in spermatogenesis and the nuclear import of the product of yki. | Importin subunit beta; Required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins. In Drosophila, may not function as a snRNP import receptor as it does not interact with components of the snRNP complex such as snRNP U1, U2, U4/U6 and Snup. | 0.985 |
| Kap-alpha1 | Karybeta3 | FBpp0074650 | FBpp0078500 | Importin subunit alpha; Karyopherin alpha1 (Kap-alpha1) encodes a protein that is involved in spermatogenesis and the nuclear import of the product of yki. | Karyopherin beta 3, isoform A; Nuclear localization sequence binding; nuclear import signal receptor activity. It is involved in the biological process described with: protein import into nucleus. | 0.772 |
| Kap-alpha1 | Nup153 | FBpp0074650 | FBpp0309144 | Importin subunit alpha; Karyopherin alpha1 (Kap-alpha1) encodes a protein that is involved in spermatogenesis and the nuclear import of the product of yki. | Nuclear pore complex protein Nup153; Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC. Essential for the nuclear import of nuclear localization signal (NLS)-containing proteins in a Importin alpha/Importin beta receptor-dependent manner. Required for nuclear import of Mad. Plays a role in chromosomal organization and gene expression regulation; stimulates transcription by promoting the formation of an open chromatin environment. Binds chromatin to nucleopor [...] | 0.982 |
| Kap-alpha1 | Ran | FBpp0074650 | FBpp0073328 | Importin subunit alpha; Karyopherin alpha1 (Kap-alpha1) encodes a protein that is involved in spermatogenesis and the nuclear import of the product of yki. | GTP-binding nuclear protein Ran; GTPase involved in nucleocytoplasmic transport, participating both to the import and the export from the nucleus of proteins and RNAs. Switches between a cytoplasmic GDP- and a nuclear GTP-bound state by nucleotide exchange and GTP hydrolysis. Nuclear import receptors such as importin beta bind their substrates only in the absence of GTP- bound RAN and release them upon direct interaction with GTP-bound RAN, while export receptors behave in the opposite way. Thereby, RAN controls cargo loading and release by transport receptors in the proper compartment [...] | 0.802 |
| Kap-alpha1 | Tnpo | FBpp0074650 | FBpp0076708 | Importin subunit alpha; Karyopherin alpha1 (Kap-alpha1) encodes a protein that is involved in spermatogenesis and the nuclear import of the product of yki. | Transportin, isoform A; Transportin (Tnpo) encodes a protein involved in Hh signalling regulation by mediating the import of the transcription factor encoded by ci into the nucleus. | 0.855 |
| Kap-alpha1 | Tnpo-SR | FBpp0074650 | FBpp0307125 | Importin subunit alpha; Karyopherin alpha1 (Kap-alpha1) encodes a protein that is involved in spermatogenesis and the nuclear import of the product of yki. | Transportin-Serine/Arginine rich (Tnpo-SR) encodes a importin-beta family protein involved in the regulation of mRNA splicing. It contributes to the import into the nucleus of serine/arginine-rich (SR) proteins, which are involved in mRNA splicing. | 0.713 |
| Kap-alpha1 | msk | FBpp0074650 | FBpp0076408 | Importin subunit alpha; Karyopherin alpha1 (Kap-alpha1) encodes a protein that is involved in spermatogenesis and the nuclear import of the product of yki. | D-Importin 7/RanBP7; Moleskin (msk) encodes an importin that contributes to protein import into the nucleus. It is involved in eye development, muscle attachment and wing cell fate specification. | 0.952 |
| Kap-alpha3 | Fs(2)Ket | FBpp0081585 | FBpp0294037 | Importin subunit alpha; Karyopherin alpha3 (Kap-alpha3) encodes a protein required for the nuclear import of the product of N; Belongs to the importin alpha family. | Importin subunit beta; Required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins. In Drosophila, may not function as a snRNP import receptor as it does not interact with components of the snRNP complex such as snRNP U1, U2, U4/U6 and Snup. | 0.955 |
| Kap-alpha3 | Karybeta3 | FBpp0081585 | FBpp0078500 | Importin subunit alpha; Karyopherin alpha3 (Kap-alpha3) encodes a protein required for the nuclear import of the product of N; Belongs to the importin alpha family. | Karyopherin beta 3, isoform A; Nuclear localization sequence binding; nuclear import signal receptor activity. It is involved in the biological process described with: protein import into nucleus. | 0.792 |
| Kap-alpha3 | Nup153 | FBpp0081585 | FBpp0309144 | Importin subunit alpha; Karyopherin alpha3 (Kap-alpha3) encodes a protein required for the nuclear import of the product of N; Belongs to the importin alpha family. | Nuclear pore complex protein Nup153; Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC. Essential for the nuclear import of nuclear localization signal (NLS)-containing proteins in a Importin alpha/Importin beta receptor-dependent manner. Required for nuclear import of Mad. Plays a role in chromosomal organization and gene expression regulation; stimulates transcription by promoting the formation of an open chromatin environment. Binds chromatin to nucleopor [...] | 0.987 |
| Kap-alpha3 | Ran | FBpp0081585 | FBpp0073328 | Importin subunit alpha; Karyopherin alpha3 (Kap-alpha3) encodes a protein required for the nuclear import of the product of N; Belongs to the importin alpha family. | GTP-binding nuclear protein Ran; GTPase involved in nucleocytoplasmic transport, participating both to the import and the export from the nucleus of proteins and RNAs. Switches between a cytoplasmic GDP- and a nuclear GTP-bound state by nucleotide exchange and GTP hydrolysis. Nuclear import receptors such as importin beta bind their substrates only in the absence of GTP- bound RAN and release them upon direct interaction with GTP-bound RAN, while export receptors behave in the opposite way. Thereby, RAN controls cargo loading and release by transport receptors in the proper compartment [...] | 0.823 |
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